Abstract
Obstructive sleep apnea (OSA) is a growing public health hazard fueled by the obesity epidemic and an aging population. Untreated sleep apnea can result in significant consequences both in the short-term and long-term. We need to educate the public to recognize the symptoms of sleep apnea and to publicize that effective treatments are available. Positive airway pressure therapy remains the gold standard currently in treating OSA. Alternative treatments include an oral appliance or surgical options. This paper discusses the pharmacologic treatment of sleep apnea: goals include medications to address the ventilatory control of breathing, treat co-morbid diseases, treat associated health problems/complaints, address special issues, such as anesthetic precautions, and propose future targets.
Keywords: Obstructive sleep apnea, treatment, pharmacotherapy, targets, CPAP, Obstructive, apnea, anesthetic, hypertension, retropharyngeal, Bariatric surgery, cholinergic, nasal congestion, acromegaly, theophylline, aminophylline, caffeine, methylxanthine, Naloxone, oxyhemoglobin
Current Pharmaceutical Design
Title: Pharmacological Treatment of Obstructive Sleep Apnea
Volume: 17 Issue: 15
Author(s): Vivien C. Abad and Christian Guilleminault
Affiliation:
Keywords: Obstructive sleep apnea, treatment, pharmacotherapy, targets, CPAP, Obstructive, apnea, anesthetic, hypertension, retropharyngeal, Bariatric surgery, cholinergic, nasal congestion, acromegaly, theophylline, aminophylline, caffeine, methylxanthine, Naloxone, oxyhemoglobin
Abstract: Obstructive sleep apnea (OSA) is a growing public health hazard fueled by the obesity epidemic and an aging population. Untreated sleep apnea can result in significant consequences both in the short-term and long-term. We need to educate the public to recognize the symptoms of sleep apnea and to publicize that effective treatments are available. Positive airway pressure therapy remains the gold standard currently in treating OSA. Alternative treatments include an oral appliance or surgical options. This paper discusses the pharmacologic treatment of sleep apnea: goals include medications to address the ventilatory control of breathing, treat co-morbid diseases, treat associated health problems/complaints, address special issues, such as anesthetic precautions, and propose future targets.
Export Options
About this article
Cite this article as:
C. Abad Vivien and Guilleminault Christian, Pharmacological Treatment of Obstructive Sleep Apnea, Current Pharmaceutical Design 2011; 17 (15) . https://dx.doi.org/10.2174/138161211796197106
DOI https://dx.doi.org/10.2174/138161211796197106 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Management of Peyronie's Disease after Collagenase (Xiaflex:<sup>®</sup>)
Current Drug Targets Matrix Metalloproteinase Inhibition in Atherosclerosis and Stroke
Current Molecular Medicine Refractory Angina Pectoris: Lessons from the Past and Current Perspectives
Current Pharmaceutical Design Reactive Oxygen-Induced Cardiac Intracellular Pathways During Ischemia and Reperfusion
Current Signal Transduction Therapy Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Induced Dyspepsia
Current Pharmaceutical Design Targeting the Human Thioredoxin System by Diverse Strategies to Treat Cancer and Other Pathologies
Recent Patents on DNA & Gene Sequences Coronary Artery Bypass Graft in HIV-Infected Patients: A Multicenter Case Control Study
Current HIV Research Comprehensive Review of Cancer Chemopreventive Agents Evaluated in Experimental Carcinogenesis Models and Clinical Trials
Current Medicinal Chemistry Recent Trends in Development of Fermented Milks
Current Nutrition & Food Science Ankylosing Spondylitis, HLA-B27, Klebsiella and “Popper Sequences”
Current Rheumatology Reviews Olive Oil and Haemostasis: Platelet Function, Thrombogenesis and Fibrinolysis
Current Pharmaceutical Design The Na+/H+ Exchanger: A Target for Cardiac Therapeutic Intervention
Current Drug Targets - Cardiovascular & Hematological Disorders Apolipoprotein A-I Mimetic Peptides for the Treatment of Coronary Artery Disease
Current Cardiology Reviews Formulation and In Vivo Evaluation of Ticagrelor Self-nanoemulsifying Drug Delivery Systems
Pharmaceutical Nanotechnology Angiotensin Mediated Oxidative Stress and Neuroprotective Potential of Antioxidants and AT1 Receptor Blockers
Mini-Reviews in Medicinal Chemistry Anthocyanins: Chemical Properties and Health Benefits: A Review
Current Nutrition & Food Science Is Glyburide Safe in Pregnancy?
Current Pharmaceutical Biotechnology Reactive Oxygen Species, Vascular Disease and Cardiovascular Surgery
Current Vascular Pharmacology Myocardial Perfusion and Coronary Vasomotor Function: Emerging Role of PET Imaging
Vascular Disease Prevention (Discontinued) Impact of Macrophages in Atherosclerosis
Current Medicinal Chemistry