Abstract
Recent data suggest a possible involvement of Aquaporins (AQPs) in pain transmission. AQPs are small membrane channel proteins involved in osmoregulation and, to date, AQP1, AQP2, AQP3, AQP4, AQP5, AQP8 and AQP9 have been found in the nervous system. Nevertheless only AQP1, AQP2 and AQP4 seem to be involved in nociception. In this review, direct and indirect evidences of the role of AQPs in pain processing will be reported.
Keywords: Aquaporins, nervous system, sensory transmission, pain transmission
Current Neuropharmacology
Title: Aquaporins in Sensory and Pain Transmission
Volume: 8 Issue: 2
Author(s): Elisa Borsani
Affiliation:
Keywords: Aquaporins, nervous system, sensory transmission, pain transmission
Abstract: Recent data suggest a possible involvement of Aquaporins (AQPs) in pain transmission. AQPs are small membrane channel proteins involved in osmoregulation and, to date, AQP1, AQP2, AQP3, AQP4, AQP5, AQP8 and AQP9 have been found in the nervous system. Nevertheless only AQP1, AQP2 and AQP4 seem to be involved in nociception. In this review, direct and indirect evidences of the role of AQPs in pain processing will be reported.
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Cite this article as:
Borsani Elisa, Aquaporins in Sensory and Pain Transmission, Current Neuropharmacology 2010; 8 (2) . https://dx.doi.org/10.2174/157015910791233187
DOI https://dx.doi.org/10.2174/157015910791233187 |
Print ISSN 1570-159X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6190 |
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