Abstract
The syntheses and transformations of 4-hydroxyquinoline-2-carboxylic acid, kynurenic acid, are reviewed, and special attention is paid to the pharmacological activities and pharmaceutical applications of its derivatives.
Keywords: Kynurenic acid, kynurenic acid derivatives, neurological disorders, schizophrenia, retinal damage, diabetes mellitus, hypertension
Current Medicinal Chemistry
Title: Syntheses, Transformations and Pharmaceutical Applications of Kynurenic Acid Derivatives
Volume: 16 Issue: 36
Author(s): F. Fulop, I. Szatmari, E. Vamos, D. Zadori, J. Toldi and L. Vecsei
Affiliation:
Keywords: Kynurenic acid, kynurenic acid derivatives, neurological disorders, schizophrenia, retinal damage, diabetes mellitus, hypertension
Abstract: The syntheses and transformations of 4-hydroxyquinoline-2-carboxylic acid, kynurenic acid, are reviewed, and special attention is paid to the pharmacological activities and pharmaceutical applications of its derivatives.
Export Options
About this article
Cite this article as:
Fulop F., Szatmari I., Vamos E., Zadori D., Toldi J. and Vecsei L., Syntheses, Transformations and Pharmaceutical Applications of Kynurenic Acid Derivatives, Current Medicinal Chemistry 2009; 16 (36) . https://dx.doi.org/10.2174/092986709789909602
DOI https://dx.doi.org/10.2174/092986709789909602 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Synthesis and Structure-Activity Relationships of 4,10-Dihydro-4-oxo-4HImidazo[ 1,2-a]Indeno[1,2-e]Pyrazine Derivatives: Highly Potent and Selective AMPA Receptor Antagonists with In Vivo Activity
Mini-Reviews in Medicinal Chemistry Melatonin, a Potential Therapeutic Agent for Smooth Muscle-Related Pathological Conditions and Aging
Current Medicinal Chemistry Patent Selections:
Recent Patents on Inflammation & Allergy Drug Discovery SIRT1 Promotes Neuronal Fortification in Neurodegenerative Diseases through Attenuation of Pathological Hallmarks and Enhancement of Cellular Lifespan
Current Neuropharmacology Applications and Synthesis of the Antiepileptic Drug Oxcarbazepine and Related Structures
Current Organic Chemistry The Glutamate Hypothesis in ALS: Pathophysiology and Drug Development
Current Medicinal Chemistry Editorial [Hot Topic: ABC Transporters in Pharmacology/Physiology and Human Diseases (Guest Editor: Zhe-Sheng (Jason) Chen)]
Current Pharmaceutical Biotechnology Neuropharmacology of Cannabinoid System: From Basic Science to Clinical Applications
Current Neuropharmacology Random Walks on Biomedical Networks
Current Proteomics The Animal Models of Dementia and Alzheimer’s Disease for Pre-Clinical Testing and Clinical Translation
Current Alzheimer Research Antiepileptic Drug Interactions - Principles and Clinical Implications
Current Neuropharmacology Histamine H3 Receptor Function and Ligands: Recent Developments
Mini-Reviews in Medicinal Chemistry 5-HT7 Receptors
Current Drug Targets - CNS & Neurological Disorders Editorial: Novel Perspectives in the Treatment of Epilepsy
Current Pharmaceutical Design Application of Human Placental Villous Tissue Explants to Study ABC Transporter Mediated Efflux of 2,4-Dinitrophenyl-S-Glutathione
Current Pharmaceutical Biotechnology Basis for the Application of Analytical Models of the Bloch NMR Flow Equations for Functional Magnetic Resonance Imaging (fMRI): A Review
Recent Patents on Medical Imaging Activation of Kir2.3 Channels by Tenidap Suppresses Epileptiform Burst Discharges in Cultured Hippocampal Neurons
CNS & Neurological Disorders - Drug Targets Could Event Related Potentials be a Key Prognostic Biomarker of Alzheimer’s Disease?
Current Alzheimer Research An Overview of Notch Signaling in Adult Tissue Renewal and Maintenance
Current Alzheimer Research University of Kentucky Sanders-Brown Healthy Brain Aging Volunteers: Donor Characteristics, Procedures and Neuropathology
Current Alzheimer Research