Abstract
This review highlights some of the recent progress that has been made in our laboratory and others in the field of trifluoromethylated (CF3) heterocyclic compounds starting from CF3-containing building blocks. Under mild reaction conditions, ethyl 4,4,4-trifluoroacetoacetate and its derivatives reacted with various organic reagents to produce CF3- containing N, O, S-heterocycles.
Keywords: Synthesis, trifluoromethylated (CF, ), ethyl 4, 4, 4-trifluoroacetoacetate, Derivatives, organic reagents
Current Organic Chemistry
Title: Recent Progress on the Synthesis of Trifluoromethylated Heterocyclic Compounds Based on ethyl 4, 4, 4-trifluoroacetoacetate and its Derivatives
Volume: 13 Issue: 10
Author(s): Shizheng Zhu, Liping Song, Guifang Jin, Baifan Dai and Jian Hao
Affiliation:
Keywords: Synthesis, trifluoromethylated (CF, ), ethyl 4, 4, 4-trifluoroacetoacetate, Derivatives, organic reagents
Abstract: This review highlights some of the recent progress that has been made in our laboratory and others in the field of trifluoromethylated (CF3) heterocyclic compounds starting from CF3-containing building blocks. Under mild reaction conditions, ethyl 4,4,4-trifluoroacetoacetate and its derivatives reacted with various organic reagents to produce CF3- containing N, O, S-heterocycles.
Export Options
About this article
Cite this article as:
Zhu Shizheng, Song Liping, Jin Guifang, Dai Baifan and Hao Jian, Recent Progress on the Synthesis of Trifluoromethylated Heterocyclic Compounds Based on ethyl 4, 4, 4-trifluoroacetoacetate and its Derivatives, Current Organic Chemistry 2009; 13 (10) . https://dx.doi.org/10.2174/138527209788680772
DOI https://dx.doi.org/10.2174/138527209788680772 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Serpin Regulation of Fibrinolytic System: Implications for Therapeutic Applications in Cardiovascular Diseases
Cardiovascular & Hematological Agents in Medicinal Chemistry Acculturation and Substance Use among Hispanic-Latino and Asian Adolescents
Current Psychiatry Reviews The Role of Functional Neuroimaging in Mild Cognitive Impairment
Current Medical Imaging The Potential Roles of Metallothionein as a Therapeutic Target for Cerebral Ischemia and Retinal Diseases
Current Pharmaceutical Biotechnology Clinical Pharmacology of Paliperidone Palmitate A Parenteral Long-Acting Formulation for the Treatment of Schizophrenia
Reviews on Recent Clinical Trials Pharmacology and Toxicology of Cannabis Derivatives and Endocannabinoid Agonists
Recent Patents on CNS Drug Discovery (Discontinued) Stem Cells in Skeletal Tissue Engineering: Technologies and Models
Current Stem Cell Research & Therapy Structural Basis of Agonist Selectivity for Different nAChR Subtypes: Insights from Crystal Structures, Mutation Experiments and Molecular Simulations
Current Pharmaceutical Design The Therapeutic Role of Lamotrigine and Topiramate in A Depressive Patient with Anxiety Symptoms and Cognitive Decline: Neurometabolic Correlates
Current Clinical Pharmacology Agonism of Peroxisome Proliferator Receptor-Gamma may have Therapeutic Potential for Neuroinflammation and Parkinsons Disease
Current Neuropharmacology Development of a Definition for the Alcohol Hangover: Consumer Descriptions and Expert Consensus
Current Drug Abuse Reviews Retinal Nerve Fiber Layer Thickness is Associated with Episodic Memory Deficit in Mild Cognitive Impairment Patients
Current Alzheimer Research Discovery of Anticancer Agents from 2-Pyrazoline-Based Compounds
Current Medicinal Chemistry Pharmacological Properties of Novel Cyclic Pentapeptides with µ-opioid Receptor Agonist Activity
Medicinal Chemistry Dimethyl Sulfoxide as an Excitatory Modulator and its Possible Role in Cancer Pain Management
Inflammation & Allergy - Drug Targets (Discontinued) AMPK As A Target in Rare Diseases
Current Drug Targets Beta-2 Agonists in Asthma: Medicine or Murderer?
Current Respiratory Medicine Reviews Patent Selections:
Recent Patents on Computer Science Chemistry in the Bioactivity of Chlorophylls: An Overview
Current Medicinal Chemistry Aβ1-40 and Aβ1-42 Plasmatic Levels In Stroke: Influence of Pre-Existing Cognitive Status and Stroke Characteristics#
Current Alzheimer Research