Abstract
This review highlights some of the recent progress that has been made in our laboratory and others in the field of trifluoromethylated (CF3) heterocyclic compounds starting from CF3-containing building blocks. Under mild reaction conditions, ethyl 4,4,4-trifluoroacetoacetate and its derivatives reacted with various organic reagents to produce CF3- containing N, O, S-heterocycles.
Keywords: Synthesis, trifluoromethylated (CF, ), ethyl 4, 4, 4-trifluoroacetoacetate, Derivatives, organic reagents
Current Organic Chemistry
Title: Recent Progress on the Synthesis of Trifluoromethylated Heterocyclic Compounds Based on ethyl 4, 4, 4-trifluoroacetoacetate and its Derivatives
Volume: 13 Issue: 10
Author(s): Shizheng Zhu, Liping Song, Guifang Jin, Baifan Dai and Jian Hao
Affiliation:
Keywords: Synthesis, trifluoromethylated (CF, ), ethyl 4, 4, 4-trifluoroacetoacetate, Derivatives, organic reagents
Abstract: This review highlights some of the recent progress that has been made in our laboratory and others in the field of trifluoromethylated (CF3) heterocyclic compounds starting from CF3-containing building blocks. Under mild reaction conditions, ethyl 4,4,4-trifluoroacetoacetate and its derivatives reacted with various organic reagents to produce CF3- containing N, O, S-heterocycles.
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Cite this article as:
Zhu Shizheng, Song Liping, Jin Guifang, Dai Baifan and Hao Jian, Recent Progress on the Synthesis of Trifluoromethylated Heterocyclic Compounds Based on ethyl 4, 4, 4-trifluoroacetoacetate and its Derivatives, Current Organic Chemistry 2009; 13 (10) . https://dx.doi.org/10.2174/138527209788680772
DOI https://dx.doi.org/10.2174/138527209788680772 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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