Abstract
Rhinosinusitis constitutes one of the most common respiratory tract diseases affecting up to 15% of the adult population in the Western world. Sinusitis is almost always accompained by inflammation of the contiguous nasal mucosa, thus the correct terminology is now rhinosinusitis. It can be classified into acute and chronic form by duration, or into acute bacterial rhinosinusitis or viral rhinosinusitis, by symptoms. This paper describes some aspects about epidemiology, pathophysiology, and predisposing factors in rhinosinusitis and nasal polyps, offering evidence based recommendations on diagnosis and first line and second line treatment. The medical management of rhinosinusitis is related to the duration and severity of symptoms and a variety of general and topical pharmacologic interventions are available, for eliminating causative factors and controlling the inflammatory and infectious components. The Authors make a review of the literature to describe the most useful anti-allergy and antiinflammatory drugs in the management of rhinosinusitis.
Keywords: Rhinisinusitis, nasal polyposis, medical management
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry
Title: Anti-Inflammatory and Anti-Allergy Drugs in Rhinosinusitis
Volume: 8 Issue: 1
Author(s): A. Moretti, A. Augurio and A. Croce
Affiliation:
Keywords: Rhinisinusitis, nasal polyposis, medical management
Abstract: Rhinosinusitis constitutes one of the most common respiratory tract diseases affecting up to 15% of the adult population in the Western world. Sinusitis is almost always accompained by inflammation of the contiguous nasal mucosa, thus the correct terminology is now rhinosinusitis. It can be classified into acute and chronic form by duration, or into acute bacterial rhinosinusitis or viral rhinosinusitis, by symptoms. This paper describes some aspects about epidemiology, pathophysiology, and predisposing factors in rhinosinusitis and nasal polyps, offering evidence based recommendations on diagnosis and first line and second line treatment. The medical management of rhinosinusitis is related to the duration and severity of symptoms and a variety of general and topical pharmacologic interventions are available, for eliminating causative factors and controlling the inflammatory and infectious components. The Authors make a review of the literature to describe the most useful anti-allergy and antiinflammatory drugs in the management of rhinosinusitis.
Export Options
About this article
Cite this article as:
Moretti A., Augurio A. and Croce A., Anti-Inflammatory and Anti-Allergy Drugs in Rhinosinusitis, Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry 2009; 8 (1) . https://dx.doi.org/10.2174/187152309787580748
DOI https://dx.doi.org/10.2174/187152309787580748 |
Print ISSN 1871-5230 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-614X |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Intracranial MR Dynamics in Clinically Diagnosed Alzheimers Disease: The Emerging Concept of “Pulse Wave Encephalopathy”
Current Alzheimer Research Medical and Dental Implications of Down Syndrome: A Review Part 1: General and Craniofacial Characteristic
Applied Clinical Research, Clinical Trials and Regulatory Affairs Neurological Disorders of Purine and Pyrimidine Metabolism
Current Topics in Medicinal Chemistry Challenges Associated with Current and Future TB Treatment
Infectious Disorders - Drug Targets The Hypothalamic-Neurohypophyseal System: Current and Future Treatment of Vasopressin and Oxytocyn Related Disorders
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery (Discontinued) GH-Inhibitory Activity of Novel Somatostatin Agonists: Potential Applications in Acromegaly
Current Medicinal Chemistry - Immunology, Endocrine & Metabolic Agents Similarities and Differences Between Renal Sympathetic Denervation and Carotid Baroreceptor Stimulation
Current Vascular Pharmacology DNA Microarrays - An Armory for Combating Infectious Diseases in the New Century
Infectious Disorders - Drug Targets Evaluation of Specific Antibody Responses in Patients with Selective IgA Deficiency and Ataxia Telangiectasia
Endocrine, Metabolic & Immune Disorders - Drug Targets Sensitization to Inhaled Allergens in Atopic Children in Jordan Capital, Amman: A Cross-sectional Study
Current Respiratory Medicine Reviews Exploring the Potential of NO-Independent Stimulators and Activators of Soluble Guanylate Cyclase for the Medical Treatment of Erectile Dysfunction
Current Pharmaceutical Design FHIT and p53 Status and Response to Platinum-Based Treatment in Advanced Non-Small Cell Lung Cancer
Current Cancer Drug Targets Incretin Pharmacology: A Review of the Incretin Effect and Current Incretin-Based Therapies
Cardiovascular & Hematological Agents in Medicinal Chemistry Current Concepts on the Management of Chordoma
Current Drug Therapy Medical Treatment of Aortic Aneurysms in Marfan Syndrome and other Heritable Conditions
Current Cardiology Reviews Targets for the Treatment of Erectile Dysfunction: Is NO/cGMP Still the Answer?
Recent Patents on Cardiovascular Drug Discovery Kawasakis Disease, Acrodynia, and Mercury
Current Medicinal Chemistry Topical Applications of Ozone and Ozonated Oils as Anti-Infective Agents: An Insight into the Patent Claims
Recent Patents on Anti-Infective Drug Discovery Gastrointestinal Motility and Functional Gastrointestinal Diseases
Current Pharmaceutical Design Vaccine Development for Group A Streptococcus Infections and Associated Diseases
Current Drug Targets