Abstract
Hypertension is estimated to affect 1 billion people worldwide, and is associated with an increased risk of cardiovascular disease and all-cause mortality. The management of high blood pressure focuses on lifestyle modifications (i.e. diet, exercise, smoking cessation) and drug therapies. Despite these strategies, many patients are still unable to maintain or control their blood pressure within desired levels. Recent research has identified isometric handgrip (IHG) training as a potential therapeutic modality. Results demonstrate a hypotensive effect of IHG training in medicated and unmedicated patients. This novel therapy may be efficacious based on low associated costs and time requirements (33 min/week). The mechanisms coupled with the attenuations in resting blood pressure remain contentious. However, recent evidence has begun to suggest that beneficial modulation of the autonomic nervous system is responsible for the positive changes in blood pressure. While further IHG research is required, the prospect of a novel non-pharmacological therapy for hypertension has major public health implications. This review will summarize the previous literature, discuss future research directions, and describe clinical significance.
Keywords: Blood pressure, hypertension, isometric exercise
Current Hypertension Reviews
Title: Isometric Handgrip Effects on Hypertension
Volume: 5 Issue: 1
Author(s): Philip J. Millar, Amanda Paashuis and Neil McCartney
Affiliation:
Keywords: Blood pressure, hypertension, isometric exercise
Abstract: Hypertension is estimated to affect 1 billion people worldwide, and is associated with an increased risk of cardiovascular disease and all-cause mortality. The management of high blood pressure focuses on lifestyle modifications (i.e. diet, exercise, smoking cessation) and drug therapies. Despite these strategies, many patients are still unable to maintain or control their blood pressure within desired levels. Recent research has identified isometric handgrip (IHG) training as a potential therapeutic modality. Results demonstrate a hypotensive effect of IHG training in medicated and unmedicated patients. This novel therapy may be efficacious based on low associated costs and time requirements (33 min/week). The mechanisms coupled with the attenuations in resting blood pressure remain contentious. However, recent evidence has begun to suggest that beneficial modulation of the autonomic nervous system is responsible for the positive changes in blood pressure. While further IHG research is required, the prospect of a novel non-pharmacological therapy for hypertension has major public health implications. This review will summarize the previous literature, discuss future research directions, and describe clinical significance.
Export Options
About this article
Cite this article as:
Millar J. Philip, Paashuis Amanda and McCartney Neil, Isometric Handgrip Effects on Hypertension, Current Hypertension Reviews 2009; 5 (1) . https://dx.doi.org/10.2174/157340209787314351
DOI https://dx.doi.org/10.2174/157340209787314351 |
Print ISSN 1573-4021 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6506 |

- Author Guidelines
- Bentham Author Support Services (BASS)
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Novel Strategies to Ameliorate Radiation Injury: A Possible Role for Tetrahydrobiopterin
Current Drug Targets Direct and Indirect Antimicrobial Activities of Neuropeptides and their Therapeutic Potential
Current Protein & Peptide Science Artemia species: An Important Tool to Screen General Toxicity Samples
Current Pharmaceutical Design TakoTsubo Cardiomyopathy A Short Review
Current Cardiology Reviews Stressing Conditions as Tools to Boost the Biosynthesis of Valuable Plant Natural Products
Recent Patents on Biotechnology Effects of Kallistatin on Oxidative Stress and Inflammation on Renal Ischemia-Reperfusion Injury in Mice
Current Vascular Pharmacology Use and Safety of Calcium Channel Blockers in Obstetrics
Current Medicinal Chemistry Protective Effects of Terpenes on the Cardiovascular System: Current Advances and Future Perspectives
Current Medicinal Chemistry New Mucoadhesive Polymeric Film for Ophthalmic Administration of Acetazolamide
Recent Patents on Drug Delivery & Formulation Role of Membrane Transporters and Metabolizing Enzymes in Ocular Drug Delivery
Current Drug Metabolism Chemoradiotherapy in Locally Advanced, Unresectable Non-Small Cell Lung Cancer
Reviews on Recent Clinical Trials Pharmacology of Adenosine A2A Receptors and Therapeutic Applications
Current Topics in Medicinal Chemistry Nitric Oxide and Teratogenesis: An Update
Current Pharmaceutical Design Thyroid Hormones and Cardiovascular System: From Bench to Bedside
Current Drug Therapy The Use of Echocardiography in the Critically Ill; The Role of FADE (Fast Assessment Diagnostic Echocardiography) Training
Current Cardiology Reviews Role of PGE2 in Blood Pressure Regulation
Current Hypertension Reviews Malignant Hypercalcemia
Current Medicinal Chemistry Pharmacological manipulation of peripheral vascular resistance in special clinical situations after pediatric cardiac surgery
Current Vascular Pharmacology Treating COPD in Older and Oldest Old Patients
Current Pharmaceutical Design PPAR Ligands Containing Stilbene Scaffold
Mini-Reviews in Medicinal Chemistry