Abstract
Pediatric cardiac surgery patients commonly suffer from alterations in vascular tone in the early post-operative period. Pharmacologic manipulation of systemic vascular resistance (SVR) can be complex in a variety of special patient situations including extremes of age, presence of left sided valvar lesions and the use of mechanical circulatory support. Familiarity with how these special circumstances alter SVR and the response to pharmacologic intervention will allow for tailored therapy and hopefully, optimized outcomes. This article addresses the eighth topic of the special issue entitled “Pharmacologic strategies with afterload reduction in low cardiac output syndrome after pediatric cardiac surgery”.
Keywords: Cardiac surgery, mechanical circulatory support, postoperative management, afterload reduction.Cardiac surgery, mechanical circulatory support, postoperative management, afterload reduction.
Current Vascular Pharmacology
Title:Pharmacological manipulation of peripheral vascular resistance in special clinical situations after pediatric cardiac surgery
Volume: 14 Issue: 1
Author(s): Michael-Alice Moga, Nguyenvu Nguyen, Mjaye L. Mazwi and John M. Costello
Affiliation:
Keywords: Cardiac surgery, mechanical circulatory support, postoperative management, afterload reduction.Cardiac surgery, mechanical circulatory support, postoperative management, afterload reduction.
Abstract: Pediatric cardiac surgery patients commonly suffer from alterations in vascular tone in the early post-operative period. Pharmacologic manipulation of systemic vascular resistance (SVR) can be complex in a variety of special patient situations including extremes of age, presence of left sided valvar lesions and the use of mechanical circulatory support. Familiarity with how these special circumstances alter SVR and the response to pharmacologic intervention will allow for tailored therapy and hopefully, optimized outcomes. This article addresses the eighth topic of the special issue entitled “Pharmacologic strategies with afterload reduction in low cardiac output syndrome after pediatric cardiac surgery”.
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Cite this article as:
Moga Michael-Alice, Nguyen Nguyenvu, Mazwi L. Mjaye and Costello M. John, Pharmacological manipulation of peripheral vascular resistance in special clinical situations after pediatric cardiac surgery, Current Vascular Pharmacology 2016; 14 (1) . https://dx.doi.org/10.2174/1570161113666151014130223
DOI https://dx.doi.org/10.2174/1570161113666151014130223 |
Print ISSN 1570-1611 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6212 |
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Cardiovascular disease still remains the leading cause of death in Chronic and End Stage Kidney Disease, accounting for more than half of all deaths in dialysis patients. During the past decade, research has been focused on novel therapeutic agents that might delay or even reverse cardiovascular disease and vascular calcification, ...read more
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