The Importance of Steroidomics in the Study of Neurodegenerative Disease and Ageing

Title: The Importance of Steroidomics in the Study of Neurodegenerative Disease and Ageing

Volume: 12 Issue: 2

Author(s): William J. Griffiths and Yuqin Wang

Affiliation:

Keywords: Mass spectrometry, tandem mass spectrometry, sterols, steroids, Alzheimer's disease, brain, CNS

Abstract: In this mini review, the importance of experimental steroidomics in the study of neurodegenerative disease and aging is discussed. Attention is focused on just one class of lipid which is based on the cyclopentanoperhydrophenanthrene ring system. Experimental methods for steroidomic analysis are reviewed, and the potential to use these methods to diagnose disease and to gain a better understanding of neurodegenerative disorders is examined.

Cite this article as:

Griffiths J. William and Wang Yuqin, The Importance of Steroidomics in the Study of Neurodegenerative Disease and Ageing, Combinatorial Chemistry & High Throughput Screening 2009; 12 (2) . https://dx.doi.org/10.2174/138620709787315472