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Current Pharmaceutical Design

Editor-in-Chief

ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Liverworts-Potential Source of Medicinal Compounds

Author(s): Y. Asakawa

Volume 14, Issue 29, 2008

Page: [3067 - 3088] Pages: 22

DOI: 10.2174/138161208786404272

Price: $65

Abstract

The bryophytes contain the Marchantiophyta (liverworts), Bryophyta (mosses) and Anthocerotophyta (hornworts) among which the Marchantiophyta contain cellular oil body and they produce a number of terpenoids, aromatic compounds and acetogenins, several of which show interesting biological activity such as allergenic contact dermatitis, insecticide, insect antifeedant, cytotoxic, piscicidal, muscle relaxing, plant growth regulatory, anti-HIV, DNA polymerase β inhibitory, anti-obesity, neurotrophic, NO production inhibitory, antimicrobial and antifungal activities. The isolation and chemical structures of biologically active compounds and their total synthesis are reviewed.

Keywords: Marchantiophyta, liverwort, terpenoids, phenolics, aroma, bitterness, cytotoxicity, anti-obesity


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