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Combinatorial Chemistry & High Throughput Screening

Editor-in-Chief

ISSN (Print): 1386-2073
ISSN (Online): 1875-5402

Automated Parallel Solid-Phase Synthesis of Non-Peptide CCR1 Receptor Antagonists

Author(s): Brad O. Buckman, Ameen Ghannam, Angela Li, Meina Liang, Raju Mohan and Howard P. Ng

Volume 5, Issue 3, 2002

Page: [249 - 251] Pages: 3

DOI: 10.2174/1386207024607284

Price: $65

Abstract

An automated, parallel, solid-phase synthesis and screening strategy using commercially available aryl acetic acids as starting materials has discovered novel, non-peptide CCR1 antagonists (Ki < 100 nM).

Keywords: solid-phase synthesis, ccri receptor antagonist


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