Abstract
The versatility and potential of reductive cyclisation as a route to 5-membered N-heterocyclic structures of diverse complexity is demonstrated through selected examples.
Keywords: heterocycles, cycloaddition, leimgruber-batcho synthesis, reducing agents, cross-coupling reaction, cytotoxicity, human lung cancer
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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