Structural Aspects of Carbohydrates and the Relation with their Biological Properties

Title: Structural Aspects of Carbohydrates and the Relation with their Biological Properties

Volume: 11 Issue: 19

Author(s): Milos Hricovini

Affiliation:

Keywords: NMR spectroscopy, crystallography, oligosaccharides, carbohydrates

Abstract: Structural diversity of carbohydrates plays a crucial role in their large variety of roles in biological systems. This paper focuses on aspects of structure and biological functions of three classes of carbohydrates, N-linked oligosaccharides, blood group oligosaccharides and glycosaminoglycans. Conformations and dynamics in solution, as well as structure of protein-carbohydrate complexes are discussed. A short overview also describes theoretical and experimental methodologies that are used in current glycobiological research, particularly high-resolution NMR spectroscopy, X-ray crystallography and methods of computational chemistry.

Cite this article as:

Hricovini Milos, Structural Aspects of Carbohydrates and the Relation with their Biological Properties, Current Medicinal Chemistry 2004; 11 (19) . https://dx.doi.org/10.2174/0929867043364414