Abstract
A review of the existing evidence on the impact of percutaneous coronary intervention (PCI) in the setting of stable coronary artery disease (CAD) indicates that in patients with chronic coronary artery disease and good left ventricular function, PCI does not confer any clear benefit in terms of hard long-term clinical outcomes, such as mortality, myocardial infarction or the need for subsequent revascularization, as compared with medical conservative treatment. By comparing the benefits against cost considerations, it seems that many percutaneous interventions that are currently performed in patients with non-acute CAD are probably not justified. Determination of the functional significance of coronary artery disease can often be a challenge. Conventional coronary angiography and imaging tests, although suitable for risk stratification, may not be satisfactory as independent guides for specific decision-making regarding the optimum management of these patients. The development of more efficient methods for the identification of coronary lesions that should be the target of coronary intervention is certainly needed.
Keywords: Percutaneopus coronary intervention, coronary angioplasty, coronary artery disease
Cardiovascular & Hematological Disorders-Drug Targets
Title: The Role of Coronary Angioplasty in the Management of Patients with Stable Coronary Artery Disease
Volume: 7 Issue: 1
Author(s): Demosthenes G. Katritsis
Affiliation:
Keywords: Percutaneopus coronary intervention, coronary angioplasty, coronary artery disease
Abstract: A review of the existing evidence on the impact of percutaneous coronary intervention (PCI) in the setting of stable coronary artery disease (CAD) indicates that in patients with chronic coronary artery disease and good left ventricular function, PCI does not confer any clear benefit in terms of hard long-term clinical outcomes, such as mortality, myocardial infarction or the need for subsequent revascularization, as compared with medical conservative treatment. By comparing the benefits against cost considerations, it seems that many percutaneous interventions that are currently performed in patients with non-acute CAD are probably not justified. Determination of the functional significance of coronary artery disease can often be a challenge. Conventional coronary angiography and imaging tests, although suitable for risk stratification, may not be satisfactory as independent guides for specific decision-making regarding the optimum management of these patients. The development of more efficient methods for the identification of coronary lesions that should be the target of coronary intervention is certainly needed.
Export Options
About this article
Cite this article as:
Katritsis G. Demosthenes, The Role of Coronary Angioplasty in the Management of Patients with Stable Coronary Artery Disease, Cardiovascular & Hematological Disorders-Drug Targets 2007; 7 (1) . https://dx.doi.org/10.2174/187152907780059092
DOI https://dx.doi.org/10.2174/187152907780059092 |
Print ISSN 1871-529X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-4063 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Roles of Renal Proximal Tubule Transport in the Pathogenesis of Hypertension
Current Hypertension Reviews Pharmacological Applications of Antioxidants: Lights and Shadows
Current Drug Targets Editorial (Hot Topic:Current Situation at Perioperative of Cardiovascular Disease Patients: New Addressing and Perioperative Optimization Techniques)
Current Pharmaceutical Design Screening the Receptorome Yields Validated Molecular Targets for Drug Discovery
Current Pharmaceutical Design Oxidative Stress-Induced Ischemic Heart Disease: Protection by Antioxidants
Current Medicinal Chemistry Incidence of Type 2 Diabetes Among Patients Exposed to the Combination of Pravastatin and Paroxetine
Current Drug Safety Mechanical Support in Cardiogenic Shock Complicating Acute Coronary Syndrome: Ready for Prime Time?
Current Vascular Pharmacology An Update on Natural Products with Carbonic Anhydrase Inhibitory Activity
Current Pharmaceutical Design Prophylaxis of Erectile Function After Radical Prostatectomy with Phosphodiesterase Type 5 Inhibitors
Current Pharmaceutical Design Targeting CD4 to Disrupt Signaling Through Membrane Rafts: Towards a Raft-Based Therapeutics
Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry (Discontinued) Biomarkers of Aging with Prognostic and Predictive Value in Non-Oncological Diseases
Current Medicinal Chemistry Gender Differences in Response to Therapy for Cardiovascular Diseases
Current Pharmacogenomics and Personalized Medicine Gastrophysics of the Oral Cavity
Current Pharmaceutical Design Menopause and its Cardiometabolic Consequences: Current Perspectives
Current Vascular Pharmacology A Novel and Significant Method for Antioxidant Activity Utilizing Microtitre-plate (Resazurin Reducing Power Assay)
Current Chemical Biology University of Kentucky Sanders-Brown Healthy Brain Aging Volunteers: Donor Characteristics, Procedures and Neuropathology
Current Alzheimer Research Effects and Perspectives of Chinese Patent Medicines for Tonifying <i>Qi</i> and Promoting Blood Circulation on Patients with Cerebral Infarction
Current Vascular Pharmacology Medical and Dental Implications of Down Syndrome: A Review Part 1: General and Craniofacial Characteristic
Applied Clinical Research, Clinical Trials and Regulatory Affairs Ultrasound Contrast Agents: Updated Data on Safety Profile
Current Pharmaceutical Design Relationships of Beta2- and Beta3--Adrenoceptor Polymorphisms with Obesity, Hypertension and Metabolic Syndrome
Current Hypertension Reviews