Particulate Systems as Adjuvants and Carriers for Peptide and Protein Antigens

Title: Particulate Systems as Adjuvants and Carriers for Peptide and Protein Antigens

Volume: 3 Issue: 4

Author(s): Ming Tao Liang, Nigel M. Davies, Joanne T. Blanchfield and Istvan Toth

Affiliation:

Keywords: Vaccine delivery, particulate delivery system, peptide or protein antigen, lipid, polymer

Abstract: The most common feature for antigen-delivery systems is their particulate nature. Together with a certain depot effect, it is the particulate nature that primarily dictates whether the antigen-delivery system will be successful in inducing a certain type and strength of immune response. In this article, we will summarize recent data on particulate delivery systems for peptide and protein antigens with a main focus on lipid or polymer-based particles, all of which possess high potential as both preventive and therapeutic vaccines for parenteral, nasal, and possibly oral administration.

Cite this article as:

Tao Liang Ming, Davies M. Nigel, Blanchfield T. Joanne and Toth Istvan, Particulate Systems as Adjuvants and Carriers for Peptide and Protein Antigens, Current Drug Delivery 2006; 3 (4) . https://dx.doi.org/10.2174/156720106778559029