Abstract
Hibernation is a unique phenotype displayed by a phylogenetically diverse group of organisms including several species of mammals and one species of primate. Here we review evidence for blood and tissue borne signaling molecules in hibernating animals, achievements in isolating and characterizing these molecules, and potential medicinal applications.
Keywords: Heterothermic, Cytoprotective, Tolerance, Hibernation induction trigger, Endogenous factors, Metabolic suppression, Suspended animation, Plasma factors
Mini-Reviews in Medicinal Chemistry
Title: Potential for Discovery of Neuroprotective Factors in Serum and Tissue from Hibernating Species
Volume: 6 Issue: 8
Author(s): Austin P.Ross and Kelly L.Drew
Affiliation:
Keywords: Heterothermic, Cytoprotective, Tolerance, Hibernation induction trigger, Endogenous factors, Metabolic suppression, Suspended animation, Plasma factors
Abstract: Hibernation is a unique phenotype displayed by a phylogenetically diverse group of organisms including several species of mammals and one species of primate. Here we review evidence for blood and tissue borne signaling molecules in hibernating animals, achievements in isolating and characterizing these molecules, and potential medicinal applications.
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Cite this article as:
P.Ross Austin and L.Drew Kelly, Potential for Discovery of Neuroprotective Factors in Serum and Tissue from Hibernating Species, Mini-Reviews in Medicinal Chemistry 2006; 6 (8) . https://dx.doi.org/10.2174/138955706777934964
DOI https://dx.doi.org/10.2174/138955706777934964 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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