Generic placeholder image

Current Pediatric Reviews

Editor-in-Chief

ISSN (Print): 1573-3963
ISSN (Online): 1875-6336

Severe Meningococcal Infections in Children and Adolescents

Author(s): Alan Graham and Brahm Goldstein

Volume 2, Issue 2, 2006

Page: [123 - 130] Pages: 8

DOI: 10.2174/157339606776894595

Price: $65

Abstract

Infection with Neisseria meningitidis remains one of the most devastating illnesses in pediatrics. Affected patients can progress from a mild viral-like illness to death within a matter of hours. Additionally, the definitive clinical diagnosis cannot be reached until the characteristic petechial rash appears, making differentiating meningococcal infection from a benign viral illness impossible. This review will discuss the epidemiology, bacteriology, pathophysiology, treatment, and potential new therapies for severe meningococcal infections in children and adolescents.

Keywords: N. meningitidis, lipopolysaccharide (LPS)-binding receptors, Polysaccharide vaccines, Anti-Sepsis Drugs, rBPI21


Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy