Login Register Cart 0
Generic placeholder image

Current Traditional Medicine

Editor-in-Chief

ISSN (Print): 2215-0838
ISSN (Online): 2215-0846

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
Review Article

A Review of Pharmacological and Phytochemical Studies on Convolvulaceae Species Rivea and Ipomea

Author(s): Pathangi Kumar, Shanthini Nachiar* and Purushoth Prabhu Thiraviam

Volume 8, Issue 2, 2022

Published on: 17 March, 2022

Article ID: e211221199205 Pages: 7

DOI: 10.2174/2215083808666211221121301

Price: $65

conference banner
Abstract

The plants of Rivea and Ipomea belong to Convolvulaceae species, identified by their funnel-like flowers and radial-shaped corolla. The stems of these plants are slender and creeper type. The plant of ipomea contains simple leaves. Whereas the leaves of Rivea are velvety in texture and have a shiny appearance. The fruits are like capsule, berry or nut containing only two seeds per one locule. Mostly Convolvulaceae species are eaten as a fresh leafy vegetable, and used traditionally to cure many ailments, such as purgative, skin disease, and as a blood purifier for arthritis, piles and urinary disorder. Both these plants possess therapeutic benefits for treating diabetes, skin infections, snakebite, and ulcer, exert antimutagenic activities, act as an immune booster and help relief respiratory congestion. In terms of phytochemical aspects, both the plants show the presence of flavonoids, terpenoids, polyphenols, carbohydrates, alkaloids, sterols and glycosides. As these plants are creepers, tribal people use their leafy parts for their nutraceutical value.

Keywords: Convolvulaceae species , Rivea hypocrateriformis , Ipomea seperia , pharmacological value, phytochemical investigation , spectroscopic analysis .

Graphical Abstract

[1]
Austin DF. University of Arizona Herbarium. 1997. Available from: http://ag.arizona.edu/herbarium/assoc/peoeple/daustin/ convolv.html (Accessed on: May 2011).
[2]
Ikhiri K, Koulodo DDD, Garba M, et al. New indolizine alkaloids from Ipomoea alba. J Nat Prod 50: 152-6.
[http://dx.doi.org/10.1021/np50050a003]
[3]
Malalavidhane S, Wickramasinghe SM, Jansz ER. An aqueous extract of the green leafy vegetable Ipomoea aquatica is as effective as the oral hypoglycaemic drug tolbutamide in reducing the blood sugar levels of Wistar rats. Phytother Res 2001; 15(7): 635-7.
[http://dx.doi.org/10.1002/ptr.851] [PMID: 11746851]
[4]
Malalavidhane TS, Wickramasinghe SM, Jansz ER. Oral hypoglycaemic activity of Ipomoea aquatica. J Ethnopharmacol 2000; 72(1-2): 293-8.
[http://dx.doi.org/10.1016/S0378-8741(00)00217-8] [PMID: 10967485]
[5]
Mamun MM, Billah MM, Ashek MA, et al. Evaluation of diuretic activity of Ipomoea aquatica (Kalmisak) in mice model study. J Med Sci 3: 395-400.
[http://dx.doi.org/10.3923/jms.2003.395.400]
[6]
Medeiros RMT, Barbosa RC, Riet-Correa F, et al. Tremorgenic syndrome in goats caused by Ipomoea asarifolia in Northeastern Brazil. Toxicon 2003; 41(7): 933-5.
[http://dx.doi.org/10.1016/S0041-0101(03)00044-8] [PMID: 12782095]
[7]
Baek NI, Ahn EM, Bang MH, Kim HY. Development of biologically active compounds from edible plant sources -I. Isolation of major components from the tuber of Ipomoea batatas Lam. J Korean Agri Chem Soc 1997; 40: 583-7.
[8]
Austin DF, Huáman Z. A synopsis of Ipomoea (Convolvulaceae) in the Americas. Taxon 1996; 45: 3-38.
[http://dx.doi.org/10.2307/1222581]
[9]
Boyd MR, Wilson BJ. Isolation and characterization of 4-ipomeanol, a lung-toxic furanoterpenoid produced by sweet potatoes (Ipomoea batatas). J Agric Food Chem 1972; 20(2): 428-30.
[http://dx.doi.org/10.1021/jf60180a066] [PMID: 5016626]
[10]
Dini I, Tenore GG, Dini A. Saponins in Ipomoea batatas tubers: Isolation, characterization, quantification and antioxidant properties. Food Chem 2009; 113: 411-9.
[http://dx.doi.org/10.1016/j.foodchem.2008.07.053]
[11]
Guan Y, Wu T, Lin M, Ye J. Determination of pharmacologically active ingredients in sweet potato (Ipomoea batatas L.) by capillary electrophoresis with electrochemical detection. J Agric Food Chem 2006; 54(1): 24-8.
[http://dx.doi.org/10.1021/jf0508347] [PMID: 16390172]
[12]
Islam MS, Yoshimoto M, Yahara S, Okuno S, Ishiguro K, Yamakawa O. Identification and characterization of foliar polyphenolic composition in sweetpotato (Ipomoea batatas L.) genotypes. J Agric Food Chem 2002; 50(13): 3718-22.
[http://dx.doi.org/10.1021/jf020120l] [PMID: 12059149]
[13]
Islam MS, Yoshimoto M, Terahara N, Yamakawa O. Anthocyanin compositions in sweetpotato (Ipomoea batatas L.) leaves. Biosci Biotechnol Biochem 2002; 66(11): 2483-6.
[http://dx.doi.org/10.1271/bbb.66.2483] [PMID: 12506993]
[14]
Islam S, Yoshimoto M, Ishiguro K, Yamakawa O. Bioactive compounds in Ipomoea batatas leaves. Acta Hortic 2003; (2): 693-9.
[http://dx.doi.org/10.17660/ActaHortic.2003.628.88]
[15]
Kusano S, Abe H. Antidiabetic activity of white skinned sweet potato (Ipomoea batatas L.) in obese Zucker fatty rats. Biol Pharm Bull 2000; 23(1): 23-6.
[http://dx.doi.org/10.1248/bpb.23.23] [PMID: 10706405]
[16]
Kusano S, Abe H, Okada A. Study of antidiabetic activity of white skinned sweet potato (Ipomoea batatas L.): comparation of normal and streptozotocin induced diabetic rats and hereditary diabetic mice. J Agri Chem Soc Japan 1998; 72: 1045-52.
[http://dx.doi.org/10.1271/nogeikagaku1924.72.1045]
[17]
Kusano S, Abe H, Tamura H. Isolation of antidiabetic components from white-skinned sweet potato (Ipomoea batatas L.). Biosci Biotechnol Biochem 2001; 65(1): 109-14.
[http://dx.doi.org/10.1271/bbb.65.109] [PMID: 11272813]
[18]
Ludvik B, Waldhäusl W, Prager R, Kautzky-Willer A, Pacini G. Mode of action of ipomoea batatas (Caiapo) in type 2 diabetic patients. Metabolism 2003; 52(7): 875-80.
[http://dx.doi.org/10.1016/S0026-0495(03)00073-8] [PMID: 12870164]
[19]
Matsui T, Ebuchi S, Kobayashi M, et al. Anti-hyperglycemic effect of diacylated anthocyanin derived from Ipomoea batatas cultivar Ayamurasaki can be achieved through the α-glucosidase inhibitory action. J Agric Food Chem 2002; 50(25): 7244-8.
[http://dx.doi.org/10.1021/jf025913m] [PMID: 12452639]
[20]
Belkin M, Fitzgerald DB, Cogan GW. Tumor-damaging capacity of plant materials. I. Plants used as cathartics. J Natl Cancer Inst 1952; 13(1): 139-55.
[PMID: 14946504]
[21]
Ferreira AA, Amaral FA, Duarte IDG, et al. Antinociceptive effect from Ipomoea cairica extract. J Ethnopharmacol 2006; 105(1-2): 148-53.
[http://dx.doi.org/10.1016/j.jep.2005.10.012] [PMID: 16307856]
[22]
de Balogh KK, Dimande AP, van der Lugt JJ, Molyneux RJ, Naudé TW, Welman WG. A lysosomal storage disease induced by Ipomoea carnea in goats in Mozambique. J Vet Diagn Invest 1999; 11(3): 266-73.
[http://dx.doi.org/10.1177/104063879901100310] [PMID: 10353359]
[23]
Ehattacharya SK, Ray A, Dasgupta B. Central nervous system depressant activity of Ipomoea carnea Jacq. Indian J Pharmacol 1975; 7: 31-4.
[24]
Górniak S, Gotardo A, Pfister J. The effects of Ipomoea carnea on neonate behavior: A study in goats. Toxicol Lett 2010; 196: S186.
[http://dx.doi.org/10.1016/j.toxlet.2010.03.634]
[25]
Haraguchi M, Gorniak SL, Ikeda K, et al. Alkaloidal components in the poisonous plant, Ipomoea carnea (Convolvulaceae). J Agric Food Chem 2003; 51(17): 4995-5000.
[http://dx.doi.org/10.1021/jf0341722] [PMID: 12903959]
[26]
Hueza IM, Fonseca ES, Paulino CA, Haraguchi M, Górniak SL. Evaluation of immunomodulatory activity of Ipomoea carnea on peritoneal cells of rats. J Ethnopharmacol 2003; 87(2-3): 181-6.
[http://dx.doi.org/10.1016/S0378-8741(03)00138-7] [PMID: 12860305]
[27]
Hueza IM, Dagli ML, Górniak SL, Paulino CA. Toxic effects of prenatal Ipomoea carnea administration to rats. Vet Hum Toxicol 2003; 45(6): 298-302.
[PMID: 14640478]
[28]
Hueza IM, Guerra JL, Haraguchi M, Naoki A, Górniak SL. The role of alkaloids in Ipomoea carnea toxicosis: A study in rats. Exp Toxicol Pathol 2005; 57(1): 53-8.
[http://dx.doi.org/10.1016/j.etp.2005.02.004] [PMID: 16089319]
[29]
Ikeda K, Kato A, Adachi I, Haraguchi M, Asano N. Alkaloids from the poisonous plant Ipomoea carnea: Effects on intracellular lysosomal glycosidase activities in human lymphoblast cultures. J Agric Food Chem 2003; 51(26): 7642-6.
[http://dx.doi.org/10.1021/jf035003k] [PMID: 14664522]
[30]
Hoffmann A. The active principles of the seeds of Rivea corymbosa and Ipomoea violacea. Harvard Univ Bot Mus Leafl 1963; 20: 194-212.
[http://dx.doi.org/10.5962/p.168542]
[31]
Hoffmann A, Tscherter H. Isolation of lysergic acid alkaloid from the Mexican magic drug Ololuiqui (Rivea corymbosa). Sandoz Lab., Basel, Switz. Experientia 1960; 16: 414-6.
[32]
Dai H, Xiong J, Zhou J, Ding Z. Chemical constituents from root of Ipomoea digitata. Yunnan Zhi Wu Yan Jiu 2000; 22: 166-8.
[33]
Matin MA, Tewari JP, Kalani DK. Pharmacological effects of paniculatin--a glycoside isolated from Ipomoea digitata Linn. J Pharm Sci 1969; 58(6): 757-9.
[http://dx.doi.org/10.1002/jps.2600580625] [PMID: 5799769]
[34]
Matin MA, Tewari JP, Kalani DK. Pharmacological investigations of Ipomoea digitata Linn. Indian J Med Sci 1969; 23(9): 479-82.
[PMID: 5371033]
[35]
Jenett-Siems K, Schimming T, Kaloga M. Pyrrolizidine alkaloids of Ipomoea hederifolia and related species. Phytochemistry 47: 1551-60.
[36]
Ejimadu IM, Ogbeide ON. Antimicrobial activities of petroleum ether and ethanol extracts of leaf, stem and root barks of Ipomoea involucrata P. Beauv. J ChemSoc Nigeria 2001; 26: 56-9.
[37]
MacLeod JK, Ward A, Oelrichs PB. Structural investigation of resin glycosides from Ipomoea lonchophylla. J Nat Prod 1997; 60(5): 467-71.
[http://dx.doi.org/10.1021/np960693q] [PMID: 9170289]
[38]
Der Marderosian A, Cho E, Chao JM. The isolation and identification of the ergoline alkaloids from Ipomoea muelleri. Planta Med 1974; 25(1): 6-16.
[http://dx.doi.org/10.1055/s-0028-1097906] [PMID: 4818014]
[39]
Der Marderosian AH, Youngken HW Jr. The distribution of indole alkaloids among certain species and varieties of Ipomoea, Rivea, and Convolvulus. Lloydia 1966; 29: 35-42.
[40]
Dawidar AM, Winternitz F, Johns SR. Structure of ipomine, a new alkaloid from Ipomoea muricata Jacq. Tetrahedron 1977; 33: 1733-4.
[http://dx.doi.org/10.1016/0040-4020(77)84050-7]
[41]
Misra AL, Tewari JD. Chemical examination of Ipomoea muricata seeds. IV. J Indian Chem Soc 1953; 30: 391-7.
[42]
Misra AL, Tewari JD. Chemical examination of Ipomoea muricata seeds. II. J Indian Chem Soc 1952; 29: 63-7.
[43]
Noda N, Kobayashi H, Miyahara K, Kawasaki T. Resin glycosides. III. Isolation and structural study of the genuine resin glycosides, muricatins I-VI, from the seeds of Ipomoea muricata. Chem Pharm Bull (Tokyo) 1988; 36: 920-9.
[http://dx.doi.org/10.1248/cpb.36.920]
[44]
Noda N, Nishi M, Miyahara K, Kawasaki T. Resin glycosides. IV. Two new resin glycosides, muricatins VII and VIII, from the seeds of Ipomoea muricata. Chem Pharm Bull (Tokyo) 1988; 36: 1707-13.
[http://dx.doi.org/10.1248/cpb.36.1707]
[45]
Noda N, Kobayashi H, Miyahara K, Kawasaki T. Resin glycosides. II. Identification and characterization of the component organic and glycosidic acids of the crude resin glycoside from the seeds of Ipomoea muricata. Chem Pharm Bull (Tokyo) 1988; 36: 627-33.
[http://dx.doi.org/10.1248/cpb.36.627]
[46]
Chérigo L, Pereda-Miranda R, Gibbons S. Bacterial resistance modifying tetrasaccharide agents from Ipomoea murucoides. Phytochemistry 2009; 70(2): 222-7.
[http://dx.doi.org/10.1016/j.phytochem.2008.12.005] [PMID: 19136125]
[47]
Noda N, Nishi M, Ono M, Miyahara K, Kawasaki T. 1985; Isolation and structures of the resin glycosides of Ipomoea orizabensis (roots) and I. muricata (seeds). Fac Pharm Sci 27: 427-34.
[48]
Noda N, Ono M, Miyahara K, Kawasaki T. Resin glycosides. I. Isolation and structure elucidation of orizabin I, II, III and IV. Genuine resin glycosides from the root of Ipomoea orizabensis. Tetrahedron 1987; 43: 3889-902.
[http://dx.doi.org/10.1016/S0040-4020(01)81671-9]
[49]
Khan MM, Ahmad F, Rastogi AK, Kidwai JR. Insulinogenic and hypoglycemic activities of Ipomoea pes-caprae. Fitoterapia 1994; 65: 231-4.
[50]
Krogh R, Kroth R, Berti C, et al. Isolation and identification of compounds with antinociceptive action from Ipomoea pes-caprae (L.) R. Br. Pharmazie 1999; 54(6): 464-6.
[PMID: 10399194]
[51]
León I, Enríquez RG, Nieto DA, et al. Pentasaccharide glycosides from the roots of Ipomoea murucoides. J Nat Prod 2005; 68(8): 1141-6.
[http://dx.doi.org/10.1021/np050075m] [PMID: 16124750]
[52]
Escobedo-Martínez C, Cruz-Morales S, Fragoso-Serrano M, Rahman MM, Gibbons S, Pereda-Miranda R. Characterization of a xylose containing oligosaccharide, an inhibitor of multidrug resistance in Staphylococcus aureus, from Ipomoea pes-caprae. Phytochemistry 2010; 71(14-15): 1796-801.
[http://dx.doi.org/10.1016/j.phytochem.2010.06.018] [PMID: 20673931]
[53]
Navarro-Ruiz A, de La Mora GP, Villanueva-Michel MT, et al. Ipopurpuroside, a new glycoside from Ipomoea purpurea. Phytochemistry 17: 451-2.
[54]
Cao S, Guza RC, Wisse JH, Miller JS, Evans R, Kingston DG. Ipomoeassins A-E, cytotoxic macrocyclic glycoresins from the leaves of Ipomoea squamosa from the Suriname rainforest. J Nat Prod 2005; 68(4): 487-92.
[http://dx.doi.org/10.1021/np049629w] [PMID: 15844934]
[55]
Enriquez RG, Leon I, Perez F, et al. Characterization, by two-dimensional NMR spectroscopy, of a complex tetrasaccharide glycoside isolated from Ipomoea stans. Can J Chem 70: 1000-8.
[http://dx.doi.org/10.1139/v92-132]
[56]
González Ramírez D, Hernández RM, Bolado C, García Delgado J. Possible anticonvulsant activity of the root of Ipomoea stans.. Salud Publica Mex 1985; 27(6): 485-91.
[PMID: 4089667]
[57]
Herrera-Ruiz M, Gutiérrez C, Enrique Jiménez-Ferrer J, Tortoriello J, Mirón G, León I. Central nervous system depressant activity of an ethyl acetate extract from Ipomoea stans roots. J Ethnopharmacol 2007; 112(2): 243-7.
[http://dx.doi.org/10.1016/j.jep.2007.03.004] [PMID: 17482785]
[58]
Noda N, Takahashi N, Kawasaki T, Miyahara K, Yang CR. Stoloniferins I-VII, resin glycosides from Ipomoea stolonifera. Phytochemistry 1994; 36(2): 365-71.
[http://dx.doi.org/10.1016/S0031-9422(00)97077-8] [PMID: 7764879]
[59]
Noda N, Takahashi N, Miyahara K, Yang CR. Stoloniferins VIII-XII, resin glycosides, from Ipomoea stolonifera. Phytochemistry 1998; 48(5): 837-41.
[http://dx.doi.org/10.1016/S0031-9422(97)00989-8] [PMID: 9664708]
[60]
Meira M. 2008; Estudofitoquímico das partesaéreas de Ipomoea subincana (Convolvulaceae). Salvador-BA 2008; 2008: 212.
[61]
Meira M, David JM, David JP, et al. Chemical constituents of Ipomoea subincana Meisn. (Convolvulaceae). Quim Nova 2008; 31: 751-4.
[http://dx.doi.org/10.1590/S0100-40422008000400007]
[62]
León-Rivera I, Mirón-López G, Estrada-Soto S, et al. Glycolipid ester-type heterodimers from Ipomoea tyrianthina and their pharmacological activity. Bioorg Med Chem Lett 2009; 19(16): 4652-6.
[http://dx.doi.org/10.1016/j.bmcl.2009.06.087] [PMID: 19596196]
[63]
Botz L, Hahn E, Szabo LG. Botanical identification of Ipomoea tricolor Cav. seed samples from Hungary and thin-layer chromatographic examination of their hallucinogen ergot alkaloids. Acta Bot Hung 1991; 36: 229-43.
[64]
Bovell-Benjamin AC. Sweet potato: A review of its past, present, and future role in human nutrition. Adv Food Nutr Res 2007; 52: 1-59.
[http://dx.doi.org/10.1016/S1043-4526(06)52001-7] [PMID: 17425943]
[65]
Bah M, Pereda-Miranda R. Detailed FAB-mass spectrometry and high resolution NMR investigations of tricolorin A-E, individual oligosaccharides from the resins of Ipomoea tricolor (Convolvulaceae). Tetrahedron 1996; 52: 13063-80.
[http://dx.doi.org/10.1016/0040-4020(96)00789-2]
[66]
Bah M, Pereda-Miranda R. Isolation and structural characterization of new ester type dimers from the resin of Ipomoea tricolor (Convolvulaceae). Tetrahedron 53: 9007-9022. Barni ST, Cechinel-Filho V, Couto AG 2009. Caracterizaçãoquímica e tecnológica das folhas, caules e planta inteira da Ipomoea pes-caprae (L.) R. Br., Convolvulaceae, comomatéria-prima farmacêutica. Rev Bras Farmacogn 1997; 19: 865-70.
[67]
Bieber LW, Silva Filho AA, Lima RMOC, et al. Anticancer and antimicrobial glycosides from Ipomoea bahiensis. Phytochemistry 25: 1077-81.
[http://dx.doi.org/10.1016/S0031-9422(00)81557-5]

Rights & Permissions Print Cite
Article Metrics
13
1
© 2024 Bentham Science Publishers | Privacy Policy