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Current Traditional Medicine

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ISSN (Print): 2215-0838
ISSN (Online): 2215-0846

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Review Article

A Review of Himalayan Medicinal Plants against Cancer

Author(s): Bhuwan C. Joshi*, Piyush Verma, Vijay Juyal and Archana N. Sah

Volume 8, Issue 1, 2022

Published on: 12 January, 2022

Article ID: e241121198254 Pages: 17

DOI: 10.2174/2215083807666211124100506

Price: $65

Abstract

Background: Plants contributed numerous novel compounds for prophylactic and curative medicine to modern science. They are an important source of natural agents used in various pharmaceutical industries. Himalayan plants are abundant in various secondary metabolites, such as anthraquinones, flavonoids, tannins, alkaloids, and terpenes. The Himalayan plants are grown in high altitudes and have around 6500 years old history as traditional medicines.

Aim: This review article systematically presents information on Himalayan medicinal plants having anti-cancer potentials.

Methodology: Around 160 articles were reviewed using online search engines, like PubMed, Scopus, Google Scholar, Web of Science, and floras of different Himalayan countries.

Results: An attempt has been made to review anti-cancer plants and active constituents isolated from several anti-cancerous plants of Himalayan regions. Eighty-three anti-cancer plants are reported in this review, and a total of twenty-two active chemical constituents, including phenolic compounds, glycosides, terpenoids, and alkaloids from the plants, were reported active against various cancer cell lines.

Conclusion: Several synthetic agents are used to cure cancer, but many undesired side effects occur during chemotherapy. Hence, the research is going on to investigate natural therapies, such as the use of plant-derived products in cancer treatment. They may reduce adverse side effects.

Keywords: Cancer, anticancer plants, bioactive compounds, molecular targets, tumour suppressor genes, chemotherapy.

Graphical Abstract

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