Deciphering the Role of Nanoparticle-based Treatment for Parkinson’s Disease

Title:Deciphering the Role of Nanoparticle-based Treatment for Parkinson’s Disease

Volume: 22 Issue: 7

Author(s): Md. Marufur Rahman Moni, Mst. Marium Begum, Md. Sahab Uddin*Ghulam Md Ashraf*

Affiliation:

• Department of Pharmacy, Southeast University, Dhaka,Bangladesh

• Pre-clinical Research Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah,Saudi Arabia

Keywords: Parkinson's disease, progressive neurodegenerative disorder, nanotechnology, nanoparticles, α-synuclein, blood-brain barrier.

Abstract: Parkinson’s disease (PD) is a progressive neurodegenerative disorder that exerts a huge burden on our society. The occurrence of this neurodegenerative disease has been increasing day-by-day. PD can be a serious concern if the patients are left untreated. However, conventional treatment has many side-effects and less bioavailability in the brain. Therefore, the necessary measurement is required to solve the limitations of PD treatment. Nanotechnology has made a major contribution to comprehend PD pathogenesis. Nanotechnology can provide efficient therapies that have reduced side-effects and increased bioavailability in the brain. This review emphasizes the emerging promise of nanoparticle-based treatment, drug delivery, and other therapeutic approaches for PD. Besides, the advantages of different approaches on nanotechnology platforms are far better over conventional therapy in the treatment of PD.

Cite this article as:

Moni Marufur Rahman Md. , Begum Marium Mst. , Uddin Sahab Md. *, Ashraf Md Ghulam*, Deciphering the Role of Nanoparticle-based Treatment for Parkinson’s Disease, Current Drug Metabolism 2021; 22 (7) . https://dx.doi.org/10.2174/1389200222666210202110129