Abstract
Derivatives of monosaccharides and oligosaccharides play important roles in biological processes. Monosaccharides are the single carbohydrate building blocks, such as glucose, xylose, and fructose. Oligosaccharides are composed of 2-10 monosaccharides, including disaccharides and trisaccharides. Moreover, monosaccharides, oligosaccharides and their derivatives are vital molecules with various biological properties, including anticancer activity, antiviral activity, insecticidal activity, antimicrobial activity, and antioxidant activity. This review covers a survey of structural modifications, biological activities, and mechanisms of action of monosaccharides, oligosaccharides and their derivatives. Additionally, their structure-activity relationships are also concluded.
Keywords: Monosaccharides, oligosaccharides, structural modifications, bioactivities, mechanisms of action, structure–activity relationship.
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Mini-Reviews in Medicinal Chemistry
Title:Advances on Monosaccharides and Oligosaccharides: Structural Modifications and Bioactivities
Volume: 21 Issue: 17
Author(s): Shaochen Li, Min Lv*, Shaoyong Zhang and Hui Xu*
Affiliation:
- College of Plant Protection, Northwest A&F University, Yangling 712100, Shaanxi Province,China
- College of Plant Protection, Northwest A&F University, Yangling 712100, Shaanxi Province,China
Keywords: Monosaccharides, oligosaccharides, structural modifications, bioactivities, mechanisms of action, structure–activity relationship.
Abstract: Derivatives of monosaccharides and oligosaccharides play important roles in biological processes. Monosaccharides are the single carbohydrate building blocks, such as glucose, xylose, and fructose. Oligosaccharides are composed of 2-10 monosaccharides, including disaccharides and trisaccharides. Moreover, monosaccharides, oligosaccharides and their derivatives are vital molecules with various biological properties, including anticancer activity, antiviral activity, insecticidal activity, antimicrobial activity, and antioxidant activity. This review covers a survey of structural modifications, biological activities, and mechanisms of action of monosaccharides, oligosaccharides and their derivatives. Additionally, their structure-activity relationships are also concluded.
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Cite this article as:
Li Shaochen , Lv Min *, Zhang Shaoyong and Xu Hui *, Advances on Monosaccharides and Oligosaccharides: Structural Modifications and Bioactivities, Mini-Reviews in Medicinal Chemistry 2021; 21 (17) . https://dx.doi.org/10.2174/1389557521666210125145321
DOI https://dx.doi.org/10.2174/1389557521666210125145321 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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