Generic placeholder image

Current Rheumatology Reviews

Editor-in-Chief

ISSN (Print): 1573-3971
ISSN (Online): 1875-6360

Research Article

Patients with Rheumatic Diseases Overlooked during COVID-19 Pandemic: How are They Doing and Behaving?

Author(s): Anass Adnine, Ilias Soussan, Khawla Nadiri, Siriman Coulibaly, Khadija Berrada, Adil Najdi and Fatima Ezzahra Abourazzak *

Volume 17, Issue 3, 2021

Published on: 28 December, 2020

Page: [318 - 326] Pages: 9

DOI: 10.2174/1573397116666201228144318

Price: $65

Abstract

Background: People with rheumatic disease may be at higher risk for more severe course with COVID- 19, and the adverse effects of drugs used to treat rheumatic diseases is a major concern.

Objective: We conducted this survey to learn about the real impact of COVID-19 pandemic on patients with rheumatic diseases.

Methods: Participants were asked to complete a questionnaire using a telephonic interview conducted by two rheumatologists. Rheumatic disease characteristics, knowledge and attitude toward COVID-19, and impacts of pandemic on rheumatology care and patient’s compliance were assessed.

Results: We included 307 patients in the survey, and rheumatoid arthris was the main rheumatic disease. Patients had mostly moderate level of knowledge about COVID-19, and patients with higher level of education were more likely to have better knowledge. Participants respected mainly recommended preventive measures. The pandemic and sanitary containment impacted strongly the rheumatology care. Over quarter of patients noted worsening of their rheumatic disease, two-thirds reported postponed or canceled medical apointments and more than three quarters postponed their laboratory tests. Patients with higher disease activity were more likely to have lack of follow-up. Medication change was noted in more than third of cases. It was mostly stopped, and DMARDs were mainly affected. Patients living in rural areas and who had canceled, or postponed their appointments were more likely to change their treatment.

Conclusion: Our data are useful to better manage rheumatic patients. Physicians are encouraged to renew contact with their patients to insure medication compliance.

Keywords: COVID 19 pandemic, rheumatic diseases, rheumatology care, medication compliance, COVID-19 Knowledge, behaviour.

[1]
Listing J, Gerhold K, Zink A. The risk of infections associated with rheumatoid arthritis, with its comorbidity and treatment. Rheumatology (Oxford) 2013; 52(1): 53-61.
[http://dx.doi.org/10.1093/rheumatology/kes305] [PMID: 23192911]
[2]
Furst DE. The risk of infections with biologic therapies for rheumatoid arthritis. Semin Arthritis Rheum 2010; 39(5): 327-46.
[http://dx.doi.org/10.1016/j.semarthrit.2008.10.002] [PMID: 19117595]
[3]
Kim AHJ, Sparks JA, Liew JW, et al. A rush to judgment? rapid reporting and dissemination of results and its consequences regarding the use of hydroxychloroquine for COVID-19. Ann Intern Med 2020; 172(12): 819-21.
[http://dx.doi.org/10.7326/M20-1223] [PMID: 32227189]
[4]
Mehta P, McAuley DF, Brown M, Sanchez E, Tattersall RS, Manson JJ. HLH Across Speciality Collaboration, UK. COVID-19: consider cytokine storm syndromes and immunosuppression. Lancet 2020; 395(10229): 1033-4.
[http://dx.doi.org/10.1016/S0140-6736(20)30628-0] [PMID: 32192578]
[5]
Konig MF, Kim AH, Scheetz MH, Graef ER, Liew JW, Simard J, et al. Baseline use of hydroxychloroquine in systemic lupus erythematosus does not preclude SARS-CoV-2 infection and severe COVID-19. Ann Rheum Dis 2020; 79(10): 1386-8.
[6]
US National Library of Medicine. 2020.https://clinicaltrials.gov/ct2/show/NCT04320615
[7]
Robinson PC, Yazdany J. The COVID-19 Global Rheumatology Alliance: collecting data in a pandemic. Nat Rev Rheumatol 2020; 16(6): 293-4.
[http://dx.doi.org/10.1038/s41584-020-0418-0] [PMID: 32242121]
[8]
Wallace ZS, Bhana S, Hausmann JS, et al. The Rheumatology Community responds to the COVID-19 pandemic: the establishment of the COVID-19 global rheumatology alliance. Rheumatology (Oxford) 2020; 59(6): 1204-6.
[http://dx.doi.org/10.1093/rheumatology/keaa191] [PMID: 32374851]
[9]
Gianfrancesco M, Hyrich KL, Al-Adely S, et al. COVID-19 Global Rheumatology Alliance. Characteristics associated with hospitalisation for COVID-19 in people with rheumatic disease: data from the COVID-19 Global Rheumatology Alliance physician-reported registry. Ann Rheum Dis 2020; 79(7): 859-66.
[http://dx.doi.org/10.1136/annrheumdis-2020-217871] [PMID: 32471903]
[10]
Serlin RC, Mendoza TR, Nakamura Y, Edwards KR, Cleeland CS. When is cancer pain mild, moderate or severe? Grading pain severity by its interference with function. Pain 1995; 61(2): 277-84.
[http://dx.doi.org/10.1016/0304-3959(94)00178-H] [PMID: 7659438]
[11]
Nikiphorou E, Radner H, Chatzidionysiou K, et al. Patient global assessment in measuring disease activity in rheumatoid arthritis: a review of the literature. Arthritis Res Ther 2016; 18(1): 251.
[http://dx.doi.org/10.1186/s13075-016-1151-6] [PMID: 27793211]
[12]
Wells GA, Boers M, Shea B, et al. Minimal disease activity for rheumatoid arthritis: a preliminary definition. J Rheumatol 2005; 32(10): 2016-24.
[PMID: 16206362]
[13]
Deodhar AA, Kumthekar A, Dubreuil M. Minimal disease activity in axial spondyloarthritis: the need of the hour and a proposal for development. Curr Opin Rheumatol 2017; 29(4): 293-7.
[http://dx.doi.org/10.1097/BOR.0000000000000387] [PMID: 28376060]
[14]
Wolfe F, Michaud K, Pincus T. A composite disease activity scale for clinical practice, observational studies, and clinical trials: the patient activity scale (PAS/PAS-II). J Rheumatol 2005; 32(12): 2410-5.
[PMID: 16331773]
[15]
Anderson J, Caplan L, Yazdany J, et al. Rheumatoid arthritis disease activity measures: American College of Rheumatology recommendations for use in clinical practice. Arthritis Care Res (Hoboken) 2012; 64(5): 640-7.
[http://dx.doi.org/10.1002/acr.21649] [PMID: 22473918]
[16]
Shaver TS, Anderson JD, Weidensaul DN, et al. The problem of rheumatoid arthritis disease activity and remission in clinical practice. J Rheumatol 2008; 35(6): 1015-22.
[PMID: 18412311]
[17]
Favalli EG, Biggioggero M, Meroni PL. Methotrexate for the treatment of rheumatoid arthritis in the biologic era: still an “anchor” drug? Autoimmun Rev 2014; 13(11): 1102-8.
[http://dx.doi.org/10.1016/j.autrev.2014.08.026] [PMID: 25172238]
[18]
World Health Organization. Clinical Management of Severe Acute Respiratory Infection When Novel Coronavirus (2019-nCoV) Infection is Suspected : Interim Guidance. 2020.
[19]
Tisoncik JR, Korth MJ, Simmons CP, Farrar J, Martin TR, Katze MG. Into the eye of the cytokine storm. Microbiol Mol Biol Rev 2012; 76(1): 16-32.
[http://dx.doi.org/10.1128/MMBR.05015-11] [PMID: 22390970]
[20]
Abdelhafiz AS, Mohammed Z, Ibrahim ME, et al. Knowledge, Perceptions, and Attitude of Egyptians Towards the Novel Coronavirus Disease (COVID-19) J Community Health 2020.
[21]
Zhong BL, Luo W, Li HM, et al. Knowledge, attitudes, and practices towards COVID-19 among Chinese residents during the rapid rise period of the COVID-19 outbreak: a quick online cross-sectional survey. Int J Biol Sci 2020; 16(10): 1745-52.
[http://dx.doi.org/10.7150/ijbs.45221] [PMID: 32226294]
[22]
Gombart AF, Pierre A, Maggini S. A review of micronutrients and the immune system-working in harmony to reduce the risk of infection. Nutrients 2020; 12 (1): 236 .
[http://dx.doi.org/10.3390/nu12010236]
[23]
Grant WB, Lahore H, McDonnell SL, Baggerly CA, French CB, Aliano JL, et al. Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths Nutrients 2020; 12 (4 ): 988 .
[24]
Chang A, Schnall AH, Law R, et al. Cleaning and Disinfectant Chemical Exposures and Temporal Associations with COVID-19 - National Poison Data System, United States, January 1, 2020-March 31, 2020. MMWR Morb Mortal Wkly Rep 2020; 69(16): 496-8.
[http://dx.doi.org/10.15585/mmwr.mm6916e1] [PMID: 32324720]
[25]
Michaud K, Wipfler K, Shaw Y, et al. Experiences of Patients With Rheumatic Diseases in the United States During Early Days of the COVID-19 Pandemic. ACR Open Rheumatol 2020; 2(6): 335-43.
[http://dx.doi.org/10.1002/acr2.11148] [PMID: 32311836]
[26]
Mikuls TR, Johnson SR, Fraenkel L, et al. Arthritis Rheumatol. American College of rheumatology guidance for the management of adult patients with rheumatic disease during the COVID-19 pandemic. 2020.
[27]
Landewé RB, Machado PM, Kroon F, et al. EULAR provisional recommendations for the management of rheumatic and musculoskeletal diseases in the context of SARS-CoV-2. Ann Rheum Dis 2020; 79(7): 851-8.
[http://dx.doi.org/10.1136/annrheumdis-2020-217877] [PMID: 32503854]
[28]
Schmeiser T, Broll M, Dormann A, et al. Einstellung von Patienten mit entzündlich-rheumatischen Erkrankungen zur immunsuppressiven Therapie im Rahmen der COVID-19 Pandemie – eine Situationsanalyse. Z Rheumatol 2020; 79(4): 379-84.
[http://dx.doi.org/10.1007/s00393-020-00800-8] [PMID: 32303821]

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy