Abstract
COVID-19 is an emerging disease that is a major threat to the global community. The main challenge in this disease is the lack of proper or proven medication. The drugs used to treat this disease are only for symptomatic treatment. Studies of other coronaviruses, such as SARS and MERS, suggest that quercetin has sufficient potential to treat COVID-19. Previous studies have shown that quercetin reduces the entry of the virus into the cell by blocking the ACE2 receptor, as well as reducing the level of interleukin-6 in SARS and MERS patients. Therefore, the aim of this review was to scrutinize the potential of quercetin as a drug in the treatment of COVID-19 from a molecular perspective.
Keywords: Quercetin, therapeutic, COVID-19, ACE2, SARS, MERS.
Current Molecular Medicine
Title:Quercetin and its Relative Therapeutic Potential Against COVID-19: A Retrospective Review and Prospective Overview
Volume: 21 Issue: 5
Author(s): Saiyad Bastaminejad and Salar Bakhtiyari*
Affiliation:
- Department of Clinical Biochemistry, Faculty of Medicine, Ilam University of Medical Sciences, Ilam,Iran
Keywords: Quercetin, therapeutic, COVID-19, ACE2, SARS, MERS.
Abstract: COVID-19 is an emerging disease that is a major threat to the global community. The main challenge in this disease is the lack of proper or proven medication. The drugs used to treat this disease are only for symptomatic treatment. Studies of other coronaviruses, such as SARS and MERS, suggest that quercetin has sufficient potential to treat COVID-19. Previous studies have shown that quercetin reduces the entry of the virus into the cell by blocking the ACE2 receptor, as well as reducing the level of interleukin-6 in SARS and MERS patients. Therefore, the aim of this review was to scrutinize the potential of quercetin as a drug in the treatment of COVID-19 from a molecular perspective.
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Cite this article as:
Bastaminejad Saiyad and Bakhtiyari Salar *, Quercetin and its Relative Therapeutic Potential Against COVID-19: A Retrospective Review and Prospective Overview, Current Molecular Medicine 2021; 21 (5) . https://dx.doi.org/10.2174/1566524020999200918150630
DOI https://dx.doi.org/10.2174/1566524020999200918150630 |
Print ISSN 1566-5240 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5666 |
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