Abstract
Coronaviruses belong to the largest group of viruses that elicit acute respiratory, enteric and systemic infections in an extensive range of hosts. A few coronaviruses from animals can progress into a new human coronavirus that can spread from person to person. On February 12, 2020, WHO officially termed the disease as Corona Virus Disease 2019 (COVID-19) and declared it a pandemic on March 11, 2020. COVID-19 is a newly emerging viral disease that has an effect on the lower respiratory tract and shows as pneumonia. Despite laborious efforts for worldwide lockdown and quarantine, the occurrence of COVID-19 continues to increase. Proper and well-designed strategies are needed to reduce social and economic consequences arisen due to this pandemic disease. Presently, there is no effective specific vaccine and anti-viral drug supported by great-level confirmation, but dexamethasone is approved in the UK for treatment of critically ill COVID-19 patients (patients on ventilators and patients requiring only oxygen) on June 16, 2020. Further research is required to clarify the factors that affect virus pathogenesis and lethal infections.
Keywords: COVID-19, Coronaviruses, diagnostics, vaccines, pandemic, infection.
[http://dx.doi.org/10.1097/01.inf.0000188166.17324.60] [PMID: 16378050]
[http://dx.doi.org/10.1007/978-1-4939-2438-7_1] [PMID: 25720466]
[http://dx.doi.org/10.1056/NEJMoa030747] [PMID: 12690091]
[http://dx.doi.org/10.1016/S0140-6736(03)13077-2] [PMID: 12711465]
[http://dx.doi.org/10.1073/pnas.0506735102] [PMID: 16169905]
[http://dx.doi.org/10.1126/science.1118391] [PMID: 16195424]
[http://dx.doi.org/10.1038/s41579-018-0118-9] [PMID: 30531947]
[http://dx.doi.org/10.1056/NEJMoa1211721] [PMID: 23075143]
[http://dx.doi.org/10.1080/01652176.2020.1727993] [PMID: 32036774]
[http://dx.doi.org/10.1056/NEJMoa030781] [PMID: 12690092]
[http://dx.doi.org/10.1128/mBio.01002-14] [PMID: 24570370]
[http://dx.doi.org/10.1056/NEJMoa030634] [PMID: 12671061]
[http://dx.doi.org/10.1172/JCI18819] [PMID: 12782660]
[http://dx.doi.org/10.1006/viro.1997.8663] [PMID: 9268167]
[http://dx.doi.org/10.1164/rccm.200305-707OE] [PMID: 12773318]
[http://dx.doi.org/10.1128/JVI.71.7.5631-5634.1997] [PMID: 9188639]
[http://dx.doi.org/10.1016/S0140-6736(20)30183-5] [PMID: 31986264]
[http://dx.doi.org/10.2139/ssrn.3524675]
[http://dx.doi.org/10.1016/j.ijid.2020.01.009] [PMID: 31953166]
[http://dx.doi.org/10.3389/fmicb.2019.00050] [PMID: 30761102]
[http://dx.doi.org/10.1001/jama.2020.2648] [PMID: 32091533]
[http://dx.doi.org/10.1016/j.drudis.2020.01.015] [PMID: 32006468]
[http://dx.doi.org/10.1016/j.ijantimicag.2020.105932] [PMID: 32145363]
[http://dx.doi.org/10.1016/j.ijantimicag.2020.105923] [PMID: 32070753]
[http://dx.doi.org/10.1056/NEJMoa2001017] [PMID: 31978945]
[http://dx.doi.org/10.1007/s11427-020-1637-5] [PMID: 32009228]
[http://dx.doi.org/10.3390/jcm9020330]
[http://dx.doi.org/10.1038/nature17200] [PMID: 26935699]
[http://dx.doi.org/doi.org/10.1101/2020.02.07.937862]
[http://dx.doi.org/doi.org/10.1038/s41586-020-2169-0]
[http://dx.doi.org/10.1093/cid/ciaa112]
[http://dx.doi.org/10.1016/j.meegid.2019.03.001] [PMID: 30844511]
[http://dx.doi.org/10.1038/s41586-020-2012-7] [PMID: 32015507]
[http://dx.doi.org/10.2807/1560-7917.ES.2020.25.3.2000045] [PMID: 31992387]
[http://dx.doi.org/10.1093/clinchem/hvaa029] [PMID: 32031583]
[http://dx.doi.org/10.1016/S0140-6736(20)30360-3] [PMID: 32151335]
[http://dx.doi.org/10.1111/resp.13196] [PMID: 29052924]
[http://dx.doi.org/10.3390/v12020135] [PMID: 31991541]
[http://dx.doi.org/10.1056/NEJMoa2001191] [PMID: 32004427]
[http://dx.doi.org/10.2807/1560-7917.ES.2020.25.4.2000058] [PMID: 32019669]
[http://dx.doi.org/10.1056/NEJMc2001468] [PMID: 32003551]
[http://dx.doi.org/10.3390/jcm9030623] [PMID: 32110875]
[http://dx.doi.org/10.1126/science.367.6477.492] [PMID: 32001631]
[http://dx.doi.org/10.1136/bmj.m308] [PMID: 31980434]
[http://dx.doi.org/10.5582/bst.2020.01020.]
[http://dx.doi.org/10.1038/d41586-020-00190-6] [PMID: 31992886]
[http://dx.doi.org/10.1016/j.jhin.2020.01.010] [PMID: 31962139]
[http://dx.doi.org/10.1038/nrmicro3143] [PMID: 24217413]
[http://dx.doi.org/10.3201/1107.050219] [PMID: 16022774]
[http://dx.doi.org/10.1016/j.ijantimicag.2020.105949] [PMID: 32205204]
[http://dx.doi.org/10.1038/nrmicro2090] [PMID: 19198616]
[http://dx.doi.org/10.1126/scitranslmed.aal3653] [PMID: 28659436]
[PMID: 12680518]
[http://dx.doi.org/10.1016/S2589-7500(20)30086-8]
[http://dx.doi.org/10.1021/acsinfecdis.0c00052]
[http://dx.doi.org/10.1016/j.jinf.2020.03.002] [PMID: 32171872]
[http://dx.doi.org/10.1016/j.ijid.2020.03.013] [PMID: 32173576]