Abstract
One of the well-recognized conditions linked to diabetes mellitus (DM) is cardiovascular disease (CVD). Those affected by DM face greater risk for early onset of CVD. Although huge strides have been made in cardiovascular therapy and prevention, with striking results in decreasing diabetesrelated coronary mortality in developed countries, the morbidity and mortality due to CVD continue to remain high among patients with diabetes. While there is an increasing incidence of cardiovascular event survivors with DM across the world, the number of DM patients with higher cardiovascular risk is predicted to soar, presenting a massive challenge for health care systems globally, including Saudi Arabia. A report of the Saudi Scientific Diabetes Society indicates that more than 50% of patients with DM die due to cardiovascular causes. In fact, Saudi Arabia globally ranks among the top 10 countries in the prevalence of diabetes. However, the incidence of CVD and its risk factors among patients with diabetes in Saudi Arabia have not yet been well documented. This review aims to present an overview of CVD among patients with DM in Saudi Arabia, through a comprehensive review of currently available published literature. The findings indicate that diabetes linked CVD burden in Saudi Arabia is expected to exponentially increase to a very high degree unless a wide-ranging epidemic control program is initiated. The findings emphasize the need for maintenance of a healthy diet accompanied by exercise, an active lifestyle and weight control measures among the population. It is essential that the health care system focus on raising awareness among the population, and implement appropriate measures for prevention, early detection and suitable management of CVD among patients with DM.
Keywords: Diabetes complication, vascular diseases, type 2 diabetes, macrovascular complications, cardiovascular disease, awareness, noncommunicable diseases, Saudi Arabia.
[PMID: 24772156]
[http://dx.doi.org/10.2174/1573399811666150724095130] [PMID: 26206092]
[http://dx.doi.org/10.1080/16549716.2019.1670014] [PMID: 31573421]
[http://dx.doi.org/10.1111/jch.13753] [PMID: 31955506]
[http://dx.doi.org/10.1155/2017/7839101] [PMID: 29238721]
[http://dx.doi.org/10.1186/s12933-018-0703-2] [PMID: 29669543]
[http://dx.doi.org/10.1056/NEJM199807233390404] [PMID: 9673301]
[http://dx.doi.org/10.1016/j.phrs.2016.09.040]
[http://dx.doi.org/10.2337/dc14-1432] [PMID: 25552418]
[http://dx.doi.org/10.1111/nyas.12044] [PMID: 23387439]
[http://dx.doi.org/10.1155/2019/2161085] [PMID: 30911551]
[http://dx.doi.org/10.4239/wjd.v6.i13.1246] [PMID: 26468341]
[http://dx.doi.org/10.1016/j.ecl.2013.09.001] [PMID: 24582090]
[http://dx.doi.org/10.1371/journal.pone.0065174] [PMID: 23935815]
[http://dx.doi.org/10.1007/s00059-016-4414-8] [PMID: 27026400]
[http://dx.doi.org/10.1161/CIRCRESAHA.115.306884] [PMID: 27230641]
[http://dx.doi.org/10.1016/j.jsha.2017.03.004] [PMID: 28983166]
[http://dx.doi.org/10.1186/s12872-019-1261-6] [PMID: 31775642]
[http://dx.doi.org/10.1155/2015/235101]
[http://dx.doi.org/10.1007/5584_2016_99] [PMID: 27815926]
[http://dx.doi.org/10.1097/MED.0000000000000044] [PMID: 24569552]
[http://dx.doi.org/10.2337/diacare.27.3.704] [PMID: 14988289]
[http://dx.doi.org/10.1155/2013/653789] [PMID: 23533715]
[http://dx.doi.org/10.1016/j.dsx.2013.06.012] [PMID: 23953177]
[http://dx.doi.org/10.7326/0003-4819-151-6-200909150-00137] [PMID: 19620144]
[http://dx.doi.org/10.1016/j.yjmcc.2008.05.006] [PMID: 18597775]
[http://dx.doi.org/10.1007/s42000-018-0014-8] [PMID: 29858856]
[http://dx.doi.org/10.4103/1319-1683.68784] [PMID: 22022666]
[http://dx.doi.org/10.4093/dmj.2012.36.6.399] [PMID: 23275932]
[http://dx.doi.org/10.4093/dmj.2011.35.5.431] [PMID: 22111032]
[http://dx.doi.org/10.1016/j.jegh.2015.07.004] [PMID: 26257035]
[http://dx.doi.org/10.1016/S0167-5273(97)00268-4] [PMID: 9476683]
[PMID: 11556038]
[PMID: 17684435]
[PMID: 11110351]
[http://dx.doi.org/10.1016/j.jsha.2015.03.003] [PMID: 26136629]
[http://dx.doi.org/10.1016/j.jval.2017.12.019] [PMID: 30005761]
[http://dx.doi.org/10.4172/2155-6156.1000575]
[http://dx.doi.org/10.2174/1573399815666190531093735] [PMID: 31146665]
[http://dx.doi.org/10.4172/2329-6607.1000650]
[http://dx.doi.org/10.2147/IJGM.S184732] [PMID: 30666149]
[http://dx.doi.org/10.1007/s00125-017-4299-y] [PMID: 28831539]
[http://dx.doi.org/10.1186/s12933-017-0574-y] [PMID: 28750645]
[http://dx.doi.org/10.1056/NEJMoa040583] [PMID: 15007110]
[http://dx.doi.org/10.1056/NEJMoa052187] [PMID: 16371630]
[http://dx.doi.org/10.1056/NEJM199309303291401] [PMID: 8366922]
[http://dx.doi.org/10.1056/NEJMoa0802743] [PMID: 18539917]