Login Register Cart 0
Generic placeholder image

Current Rheumatology Reviews

Editor-in-Chief

ISSN (Print): 1573-3971
ISSN (Online): 1875-6360

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
General Research Article

Comparison of Non-radiographic Axial Spondyloarthritis and Ankylosing Spondyltis from a Single Rheumatology Hospital in Morocco

Author(s): Nessrine Akasbi*, Siar Nihad, Zoukal Sofia, El Kohen Khadija and Harzy Taoufik

Volume 16, Issue 3, 2020

Page: [240 - 244] Pages: 5

DOI: 10.2174/1573397115666190222195923

Price: $65

Abstract

Background: According to the new classification criteria developed by The Assessment of SpondyloArthritis International Society, patients with axial spondyloarthritis (axSpA) can be classified in 2 subgroups: Patients with radiographic axial spondyloarthritis: ankylosing spondylitis patients (AS) and those with non-radiographic axial spondyloarthritis (nr-axSpA).

Objective: The aim of the present study is to describe and discuss the differences and similarities between the two subgroups.

Patients and Methods: A cross-sectional study was conducted in a single rheumatology hospital in Morocco. These included patients diagnosed as having axial spondyloarthritis according to ASAS criteria 2010, during a period of 6 years. The AS and the nr-axSpA subgroups were compared for the various axSpA-related variables.

Results: Of the 277 patients with a diagnosis of axial SpA who were included in this study, 160 had AS and 117 had nr-axSpA. AS and nr-ax-SpA shared a similar age at diagnosis, similar prevalence of low back pain, lumbar stiffness, extra-articular manifestations, BASDAI and BASFI. In the multivariate analysis, AS patients were mainly male with cervical stiffness, enthesitis, coxitis and high level of ESR (erythrocyte sedimentation rate). The females generally had a family history of SpA and arthritis and were associated to the nr-axSpA form in the univariate analysis.

Conclusion: This was the first study to characterise patients with AS and nr-axSpA in Morocco. Consistent with other studies published, this study showed that patients with nr-axSpA and patients with AS shared a comparable degree of disease burden.

Keywords: Axial spondyloarthritis, non-radiographic axial spondyloarthritis, ankylosing spondylitis, moroccan patients, erythrocyte sedimentation rate, rheumatic disease.

« Previous Next »
[1]
Sieper J, Poddubnyy D. Axial spondyloarthritis. Lancet 2017; 390(10089): 73-84.
[http://dx.doi.org/10.1016/S0140-6736(16)31591-4] [PMID: 28110981]
[2]
Van Der Linden S, Valkenburg HA, Cats A. Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria. Arthritis Rheum 1984; 27(4): 361-8.
[http://dx.doi.org/10.1002/art.1780270401] [PMID: 6231933]
[3]
Rudwaleit M, van der Heijde D, Landewé R, et al. The development of assessment of spondyloarthritis international Society classification criteria for axial spondyloarthritis (part II): validation and final selection. Ann Rheum Dis 2009; 68(6): 777-83.
[http://dx.doi.org/10.1136/ard.2009.108233] [PMID: 19297344]
[4]
Poddubnyy D, Sieper J. Similarities and differences between nonradiographic and radiographic axial spondyloarthritis: a clinical, epidemiological and therapeutic assessment. Curr Opin Rheumatol 2014; 26(4): 377-83.
[http://dx.doi.org/10.1097/BOR.0000000000000071] [PMID: 24807404]
[5]
Rostom S, Benbouaaza K, Amine B, et al. Psychometric evaluation of the Moroccan version of the Bath Ankylosing Spondylitis Functional Index (BASFI) and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) for use in patients with ankylosing spondylitis. Clin Rheumatol 2010; 29(7): 781-8.
[http://dx.doi.org/10.1007/s10067-010-1431-5] [PMID: 20383548]
[6]
Stolwijk C, Boonen A, van Tubergen A, Reveille JD. Epidemiology of spondyloarthritis. Rheum Dis Clin North Am 2012; 38(3): 441-76.
[http://dx.doi.org/10.1016/j.rdc.2012.09.003] [PMID: 23083748]
[7]
Sieper J, Srinivasan S, Zamani O, et al. Comparison of two referral strategies for diagnosis of axial spondyloarthritis: the Recognising and Diagnosing Ankylosing Spondylitis Reliably (RADAR) study. Ann Rheum Dis 2013; 72(10): 1621-7.
[http://dx.doi.org/10.1136/annrheumdis-2012-201777] [PMID: 23065731]
[8]
Rudwaleit M, Haibel H, Baraliakos X, et al. The early disease stage in axial spondylarthritis: results from the German Spondyloarthritis Inception Cohort. Arthritis Rheum 2009; 60(3): 717-27.
[http://dx.doi.org/10.1002/art.24483] [PMID: 19248087]
[9]
Kiltz U, Baraliakos X, Karakostas P, et al. Do patients with non-radiographic axial spondylarthritis differ from patients with ankylosing spondylitis? Arthritis Care Res (Hoboken) 2012; 64(9): 1415-22.
[http://dx.doi.org/10.1002/acr.21688] [PMID: 22505331]
[10]
Mease JP, Van der heijde D, Karki C, et al. Characterization of Patients with ankylosing spondylitis and nonradiographic axial spondyloarthritis in the us-based corrona registry. Arthritis Care Res 2018; 70(11): 1661-70.
[11]
Jeong H, Yoon JY, Park EJ, et al. Clinical characteristics of nonradiographic axial spondyloarthritis in Korea: a comparison with ankylosing spondylitis. Int J Rheum Dis 2015; 18(6): 661-8.
[http://dx.doi.org/10.1111/1756-185X.12458] [PMID: 25195726]
[12]
Malaviya AN, Kalyani A, Rawat R, Gogia SB. Comparison of patients with ankylosing spondylitis (AS) and non-radiographic axial spondyloarthritis (nr-axSpA) from a single rheumatology clinic in New Delhi. Int J Rheum Dis 2015; 18(7): 736-41.
[http://dx.doi.org/10.1111/1756-185X.12579] [PMID: 26172961]
[13]
Wallman JK, Kapetanovic MC, Petersson IF, Geborek P, Kristensen LE. Comparison of non-radiographic axial spondyloarthritis and ankylosing spondylitis patients--baseline characteristics, treatment adherence, and development of clinical variables during three years of anti-TNF therapy in clinical practice. Arthritis Res Ther 2015; 17: 378.
[http://dx.doi.org/10.1186/s13075-015-0897-6] [PMID: 26703005]
[14]
Wallis D, Haroon N, Ayearst R, Carty A, Inman RD. Ankylosing spondylitis and nonradiographic axial spondyloarthritis: part of a common spectrum or distinct diseases? J Rheumatol 2013; 40(12): 2038-41.
[http://dx.doi.org/10.3899/jrheum.130588] [PMID: 24187102]
[15]
Poddubnyy D, Rudwaleit M, Haibel H, et al. Rates and predictors of radiographic sacroiliitis progression over 2 years in patients with axial spondyloarthritis. Ann Rheum Dis 2011; 70(8): 1369-74.
[http://dx.doi.org/10.1136/ard.2010.145995] [PMID: 21622969]
[16]
Chung HY, Machado P, van der Heijde D, D’Agostino M-A, Dougados M. Smokers in early axial spondyloarthritis have earlier disease onset, more disease activity, inflammation and damage, and poorer function and health-related quality of life: results from the DESIR cohort. Ann Rheum Dis 2012; 71(6): 809-16.
[http://dx.doi.org/10.1136/annrheumdis-2011-200180] [PMID: 21989541]
[17]
Lee W, Reveille JD, Weisman MH. Women with ankylosing spondylitis: a review. Arthritis Rheum 2008; 59(3): 449-54.
[http://dx.doi.org/10.1002/art.23321] [PMID: 18311755]
[18]
Wanders AJ, Landewé RB, Spoorenberg A, et al. What is the most appropriate radiologic scoring method for ankylosing spondylitis? A comparison of the available methods based on the Outcome Measures in Rheumatology Clinical Trials filter. Arthritis Rheum 2004; 50(8): 2622-32.
[http://dx.doi.org/10.1002/art.20446] [PMID: 15334477]
[19]
Bahiri R, Ichchou L, Bezza A, Khalil A, Sedrati B, Larhrissi S, et al. Recommendations of the Moroccan Society of Rheuma-tology (SMR) for the therapeutic management of patients with severe ankylosing spondylitis (SpA). Rev Mar Rhum 2017; 39: 3-18.
[20]
van der Heijde D, Ramiro S, Landewé R, et al. 2016 update of the ASAS-EULAR management recommendations for axial spondyloarthritis. Ann Rheum Dis 2017; 76(6): 978-91.
[http://dx.doi.org/10.1136/annrheumdis-2016-210770] [PMID: 28087505]
[21]
Braun J, van den Berg R, Baraliakos X, et al. 2010 update of the ASAS/EULAR recommendations for the management of ankylosing spondylitis. Ann Rheum Dis 2011; 70(6): 896-904.
[http://dx.doi.org/10.1136/ard.2011.151027] [PMID: 21540199]
[22]
Baraliakos X, Braun J. Non-radiographic axial spondyloarthritis and ankylosing spondylitis: what are the similarities and differences? RMD Open 2015; 1(Suppl. 1).: e000053.
[http://dx.doi.org/10.1136/rmdopen-2015-000053]] [PMID: 26557375]
[23]
Braun J, Baraliakos X, Kiltz U. Non-radiographic axial spondyloarthritis: a classification or a diagnosis? Clin Exp Rheumatol 2016; 34(1)(Suppl. 95): S5-6.
[PMID: 25897627]
[24]
Poddubnyy D, Sieper J. Similarities and differences between nonradiographic and radiographic axial spondyloarthritis: a clinical, epidemiological and therapeutic assessment. Curr Opin Rheumatol 2014; 26(4): 377-83.
[http://dx.doi.org/10.1097/BOR.0000000000000071] [PMID: 24807404]
[25]
Deodhar A, Strand V, Kay J, Braun J. The term ‘non-radiographic axial spondyloarthritis’ is much more important to classify than to diagnose patients with axial spondyloarthritis. Ann Rheum Dis 2016; 75(5): 791-4.
[http://dx.doi.org/10.1136/annrheumdis-2015-208852] [PMID: 26768406]

Rights & Permissions Print Cite
Article Metrics
15
© 2024 Bentham Science Publishers | Privacy Policy