[1]
Coleman, J.E. Structure and mechanism of alkaline phosphatase. Annu. Rev. Biophys. Biomol. Struct., 1992, 21, 441.
[2]
Duarte, F.; Amrein, B.A.; Kamerlin, S.C.L. Modeling catalytic promiscuity in the alkaline phosphatase superfamily. Phys. Chem. Chem. Phys., 2013, 15, 11160.
[3]
Pabis, A.; Kamerlin, S.C.L. Promiscuity and electrostatic flexibility in the alkaline phosphatase superfamily. Curr. Opin. Struct. Biol., 2016, 37, 14.
[4]
Al-Rashida, M.; Iqbal, J. Therapeutic potentials of ecto-nucleoside triphosphate diphosphohydrolase, ecto-nucleotide pyrophosphatase/phosphodiesterase, ecto-5′-nucleotidase, and alkaline phosphatase inhibitors. Med. Res. Rev., 2014, 34, 703.
[5]
Zimmermann, H.; Zebisch, M.; Sträter, N. Cellular function and molecular structure of ecto-nucleotidases. Purinergic Signal., 2012, 8, 437.
[6]
Bonan, C.D. Ectonucleotidases and nucleotide/nucleoside transporters as pharmacological targets for neurological disorders. CNS Neurol. Disord. Drug Targets, 2012, 11, 739.
[7]
Holtz, K.M.; Kantrowitz, E.R. The mechanism of the alkaline phosphatase reaction: Insights from NMR, crystallography and site‐specific mutagenesis. FEBS Lett., 1999, 462, 7.
[8]
Millán, J.L. Alkaline phosphatases. Purinergic Signal., 2006, 2, 335.
[9]
Hotton, D.; Mauro, N.; Lézot, F.; Forest, N.; Berdal, A. Differential expression and activity of tissue-nonspecific alkaline phosphatase (TNAP) in rat odontogenic cells in vivo. J. Histochem. Cytochem., 1999, 47, 1541.
[10]
Orimo, H. The mechanism of mineralization and the role of alkaline phosphatase in health and disease. J. Nippon Med. Sch., 2010, 77, 4.
[11]
Buchet, R.; Millán, J.L.; Magne, D. Multisystemic functions of alkaline phosphatases. Phosphatase Modulators. Methods Mol. Biol., 2013, 27.
[12]
Bobryshev, Y.V.; Orekhov, A.N.; Sobenin, I.; Chistiakov, D.A. Role of bone-type tissue-nonspecific alkaline phosphatase and PHOSPO1 in vascular calcification. Curr. Pharm. Des., 2014, 20, 5821.
[13]
Millán, J.L. The role of phosphatases in the initiation of skeletal mineralization. Calcif. Tissue Int., 2013, 93, 299.
[14]
Yang, J-H.; Oh, K-J.; Pandher, D.S. Hydroxyapatite crystal deposition causing rapidly destructive arthropathy of the hip joint. Indian J. Orthop., 2011, 45, 569.
[15]
Lomashvili, K.; Garg, P.; Narisawa, S.; Millan, J.; O’neill, W. Upregulation of alkaline phosphatase and pyrophosphate hydrolysis: Potential mechanism for uremic vascular calcification. Kidney Int., 2008, 73, 1024.
[16]
Narisawa, S.; Harmey, D.; Yadav, M.C.; O’Neill, W.C.; Hoylaerts, M.F.; Millán, J.L. Novel inhibitors of alkaline phosphatase suppress vascular smooth muscle cell calcification. J. Bone Miner. Res., 2007, 22, 1700.
[17]
Shioi, A.; Katagi, M.; Okuno, Y.; Mori, K.; Jono, S.; Koyama, H.; Nishizawa, Y. Induction of bone-type alkaline phosphatase in human vascular smooth muscle cells. Circ. Res., 2002, 91, 9.
[18]
Denu, R.A.; Hematti, P. Effects of oxidative stress on mesenchymal stem cell biology. Oxid. Med. Cell. Longev., 2016, Article ID 2989076.
[19]
Zhou, X.; Cui, Y.; Zhou, X.; Han, J. Phosphate/pyrophosphate and MV-related proteins in mineralisation: Discoveries from mouse models. Int. J. Biol. Sci., 2012, 8, 778.
[20]
Al-Rashida, M.; Iqbal, J. Inhibition of alkaline phosphatase: An emerging new drug target. Mini Rev. Med. Chem., 2015, 15, 41.
[21]
Al-Rashida, M.; Raza, R.; Abbas, G.; Shah, M.S. Kostakis, George E.; Lecka, J.; Sévigny, J.; Muddassar, M.; Papatriantafyllopoulou, C.; Iqbal, J. Identification of novel chromone based sulfonamides as highly potent and selective inhibitors of alkaline phosphatases. Eur. J. Med. Chem., 2013, 66, 438.
[22]
Salar, U.; Khan, K.M.; Iqbal, J.; Ejaz, S.A.; Hameed, A.; al-Rashida, M.; Perveen, S.; Tahir, M.N. Coumarin sulfonates: New alkaline phosphatase inhibitors; in vitro and in silico studies. Eur. J. Med. Chem., 2017, 131, 29.
[23]
Salar, U.; Khan, K.M.; Jabeen, A.; Faheem, A.; Fakhri, M.I.; Saad, S.M.; Perveen, S.; Taha, M.; Hameed, A. Coumarin sulfonates: As potential leads for ROS inhibition. Bioorg. Chem., 2016, 69, 37.
[24]
Saeed, Aamer. Ejaz, S.A.; Khurshid, A.; Hassan, S.; al-Rashida, M.; Latif, M.; Lecka, J.; Sévigny, J.; Iqbal, J. Synthesis, characterization and biological evaluation of N-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)benzamides. RSC Adv, 2015, 5, 86428.
[25]
Davis, I.W.; Murray, L.W.; Richardson, J.S.; Richardson, D.C. PMCID: PMC441536 Mol Probity: Structure validation and all-atom contact analysis for nucleic acids and their complexes. Nucleic Acids Res., 2004, 32, W615.
[26]
Lüthy, R.; Bowie, J.U.; Eisenberg, D. VERIFY3D: Assessment of protein models with three-dimensional profiles. Methods Enzymol., 1997, 277, 396.
[27]
Delaney, J.S. ESOL: Estimating aqueous solubility directly from molecular structure. J. Chem. Inf. Comput. Sci., 2004, 44, 1000.
[28]
Hughes, J.D.; Blagg, J.; Price, D.A.; Bailey, S.; DeCrescenzo, G.A.; Devraj, R.V.; Ellsworth, E.; Fobian, Y.M.; Gibbs, M.E.; Gilles, R.W. Physiochemical drug properties associated with in vivo toxicological outcomes. Bioorg. Med. Chem. Lett., 2008, 18, 4872.
[29]
Veber, D.F.; Johnson, S.R.; Cheng, H-Y.; Smith, B.R.; Ward, K.W.; Kopple, K.D. Molecular properties that influence the oral bioavailability of drug candidates. J. Med. Chem., 2002, 45, 2615.
[32]
Accelrys Software Inc. Discovery Studio Modeling Environment, Release 4.0; Accelrys Software Inc.: San Diego, 2013.
[33]
Bravo, Y.; Teriete, P.; Dhanya, R-P.; Dahl, R.; San Lee, P.; Kiffer-Moreira, T.; Ganji, S.R.; Sergienko, E.; Smith, L.H.; Farquharson, C. Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1. Bioorg. Med. Chem. Lett., 2014, 24, 4308.