Abstract
Introduction: Phenol or carbolic acid is an aromatic compound and has mild acidic nature. In 1834, it was firstly achieved by Friedlieb Ferdinand by the destructive extraction of coal tar. It is used as a significant raw material in quite a lot of chemical manufacturing. Phenol derivatives have been found to possess Antimicrobial, Analgesic, Anti-inflammatory, Antioxidant, Anti-convulsant, Anti-cancer, Anesthetic, Antiseptic and Disinfecticides, Anti-tubercular and Anti-parkinson activity. Several more compounds have been discovered and many are still being focused.
Conclusion: The main objective of this article is to show up the different derivatives and the pharmacological activities of Phenol and its derivatives. It can be concluded that Phenol and its derivatives posses significant therapeutic functions and many potent derivatives are still to be discovered.
Keywords: Analgesic activity, anti-cancer activity, anti-convulsant activity, anti-inflammatory activity, anti-microbial activity, anti-oxidant activity, anti-tubercular activity, phenol.
Graphical Abstract
Letters in Organic Chemistry
Title:Biological Importance of Phenol Derivatives as Potent Bioactive Compound: A Review
Volume: 15 Issue: 4
Author(s): Arvind Kumar*Arun K. Mishra
Affiliation:
- Drug Design Laboratory, School of Pharmaceutical Sciences, IFTM University, Moradabad - 244001, Uttar Pradesh,India
Keywords: Analgesic activity, anti-cancer activity, anti-convulsant activity, anti-inflammatory activity, anti-microbial activity, anti-oxidant activity, anti-tubercular activity, phenol.
Abstract: Introduction: Phenol or carbolic acid is an aromatic compound and has mild acidic nature. In 1834, it was firstly achieved by Friedlieb Ferdinand by the destructive extraction of coal tar. It is used as a significant raw material in quite a lot of chemical manufacturing. Phenol derivatives have been found to possess Antimicrobial, Analgesic, Anti-inflammatory, Antioxidant, Anti-convulsant, Anti-cancer, Anesthetic, Antiseptic and Disinfecticides, Anti-tubercular and Anti-parkinson activity. Several more compounds have been discovered and many are still being focused.
Conclusion: The main objective of this article is to show up the different derivatives and the pharmacological activities of Phenol and its derivatives. It can be concluded that Phenol and its derivatives posses significant therapeutic functions and many potent derivatives are still to be discovered.
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Cite this article as:
Kumar Arvind *, Mishra K. Arun , Biological Importance of Phenol Derivatives as Potent Bioactive Compound: A Review, Letters in Organic Chemistry 2018; 15 (4) . https://dx.doi.org/10.2174/1570178614666171130155539
DOI https://dx.doi.org/10.2174/1570178614666171130155539 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |

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