Glaucoma Drug Therapy in Pregnancy: Literature Review and Teratology Information Service (TIS) Case Series

Title:Glaucoma Drug Therapy in Pregnancy: Literature Review and Teratology Information Service (TIS) Case Series

Volume: 13 Issue: 1

Author(s): Marcella Pellegrino*, Luisa D`Oria, Carmen De Luca, Giacomina Chiaradia, Angelo Licameli, Caterina Neri, Marta Nucci, Daniela Visconti, Alessandro Caruso and Marco De Santis

Affiliation:

• Teratology Information Service, Department of Obstetrics and Gynecology, Fetal Diagnosis and Therapy Unit, Catholic University of Sacred Heart, Policlinico A. Gemelli Hospital, Rome,Italy

Keywords: Congenital anomalies, drugs, glaucoma, pregnancy, prenatal diagnosis, Teratology Information Service (TIS).

Abstract: Background: There are many contradictions about pregnancy and fetal/neonatal outcomes after topical use of timolol alone or timolol in combination with other antiglaucoma medications.

Methods: Seventy-five pregnant women exposed to antiglaucoma medications were followed prospectively by phone interviews. 27 women used timolol as monotherapy, 48 women used timolol as a part of multidrug therapy. We selected a control group of 187 healthy pregnant women.

Results: Topical use of timolol alone or timolol in combination with other antiglaucoma medications does not influence pregnancy or fetal/neonatal outcomes.

Conclusion: Beta-blocker is the first choice treatment for glaucoma in pregnancy but, when necessary, multidrug therapy should not to be excluded.

Cite this article as:

Pellegrino Marcella *, D`Oria Luisa , De Luca Carmen , Chiaradia Giacomina , Licameli Angelo, Neri Caterina , Nucci Marta, Visconti Daniela , Caruso Alessandro and De Santis Marco , Glaucoma Drug Therapy in Pregnancy: Literature Review and Teratology Information Service (TIS) Case Series, Current Drug Safety 2018; 13 (1) . https://dx.doi.org/10.2174/1574886312666171030125804