Recent Progress in Biological Activities of Indole and Indole Alkaloids

Title:Recent Progress in Biological Activities of Indole and Indole Alkaloids

Volume: 18 Issue: 1

Author(s): Thokchom Prasanta Singh and Okram Mukherjee Singh*

Affiliation:

• Chemistry Department, Manipur University, Canchipur-795 003, Manipur,India

Keywords: Anti-cancer, anti-HIV, anti-microbial, anti-oxidant, biological activities, indole.

Abstract: The indole scaffold is found in a wide range of bioactive heterocycles and natural products. Moreover, the indole moiety is considered as the active principle in several alkaloids such as mitomycin C and reserpine. Thus, over the past decade, chemists are increasingly attracted towards the studies on the pharmacological and therapeutic activities of indole containing compounds. Furthermore, the molecular structures of well-known drugs such as sumatriptan, tadalafil, fluvastatin and rizatriptan are based on indole frameworks.

This mini-review covers some of the significant and recent achievements of indole derivatives with respect to their biological activities up to 2015.

Cite this article as:

Singh Prasanta Thokchom and Singh Mukherjee Okram *, Recent Progress in Biological Activities of Indole and Indole Alkaloids, Mini-Reviews in Medicinal Chemistry 2018; 18 (1) . https://dx.doi.org/10.2174/1389557517666170807123201