Abstract
Background: Epilepsy is the second most common disease caused by multiple factors and characterized by an excessive discharge of certain neurons in the nervous system. Cerebrovascular disease, including stroke, is viewed as the most common cause of epilepsy in the elderly population, accounting for 30%-50% of the newly diagnosed cases of epilepsy cases in this age group.
Methods: Data were collected from Web of Science, Medline, Pubmed, Scopus, through searching of these keywords: “Stroke” and “epilepsy”.
Results: Depending on the underlying cerebrovascular disease, 3%-30% of patients after stroke may develop post-stroke epilepsy (PSE), which has a negative effect on stroke prognosis and the quality of life.
Conclusion: In this review, we summarized new aspects emerging from research into PSE, including definition, epidemiology, risk factors, mechanism, accessory examination and treatment strategies for post-stroke epilepsy, which will enrich our knowledge of this disorder.
Keywords: Epilepsy, stroke, seizure, post-stroke epilepsy, risk factor, brain.
Graphical Abstract
Current Neuropharmacology
Title:The Progress of Epilepsy after Stroke
Volume: 16 Issue: 1
Author(s): Yinghao Zhao, Xiangyan Li, Kun Zhang, Ti Tong*Ranji Cui*
Affiliation:
- Department of Thoracic Surgery, The Second Hospital of Jilin University; Jilin Provincial Key Laboratory on Molecular and Chemical Genetic, Changchun, Jilin,China
- Jilin Provincial Key Laboratory on Molecular and Chemical Genetic, The Second Hospital of Jilin University, 218 Ziqiang Street, Changchun 130041,China
Keywords: Epilepsy, stroke, seizure, post-stroke epilepsy, risk factor, brain.
Abstract: Background: Epilepsy is the second most common disease caused by multiple factors and characterized by an excessive discharge of certain neurons in the nervous system. Cerebrovascular disease, including stroke, is viewed as the most common cause of epilepsy in the elderly population, accounting for 30%-50% of the newly diagnosed cases of epilepsy cases in this age group.
Methods: Data were collected from Web of Science, Medline, Pubmed, Scopus, through searching of these keywords: “Stroke” and “epilepsy”.
Results: Depending on the underlying cerebrovascular disease, 3%-30% of patients after stroke may develop post-stroke epilepsy (PSE), which has a negative effect on stroke prognosis and the quality of life.
Conclusion: In this review, we summarized new aspects emerging from research into PSE, including definition, epidemiology, risk factors, mechanism, accessory examination and treatment strategies for post-stroke epilepsy, which will enrich our knowledge of this disorder.
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Cite this article as:
Zhao Yinghao , Li Xiangyan , Zhang Kun , Tong Ti *, Cui Ranji*, The Progress of Epilepsy after Stroke, Current Neuropharmacology 2018; 16 (1) . https://dx.doi.org/10.2174/1570159X15666170613083253
DOI https://dx.doi.org/10.2174/1570159X15666170613083253 |
Print ISSN 1570-159X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6190 |
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