Abstract
Background: Subcutaneous phaeohyphomycosis is an infection caused by melanized fungi and is increasingly reported among immunosuppressive patients. The most commonly cited etiologic agent is Exophiala jeanselmei, followed by Alternaria spp. We present a case of subcutaneous phaeohyphomycosis in a 48-yearold woman, with a history of lepromatous leprosy, using corticosteroid in immunosuppressive doses due to a type 2 repetitive reaction leprosy outbreak.
Result and Discussion: The diagnosis was confirmed by fine-needle aspiration of the secretion, with subsequent direct mycological observations, culture and molecular analysis. The species agent was identified by culture and nucleotide sequences of ribosomal DNA as Exophiala dermatitidis.Keywords: Dermatomycoses, leprosy, phaeohyphomycosis, Exophiala dermatitidis, mycological, DNA.
Graphical Abstract
Infectious Disorders - Drug Targets
Title:A Case of Subcutaneous Phaeohyphomycosis Associated with Leprosy
Volume: 17 Issue: 3
Author(s): Márcia M. R. Teixeira, Claudia B. Assunção, Sandra Lyon, Renata R. Gomes, Hyllo B.M. Junior, Fabiana Rocha-Silva, Sônia M. de Figueiredo, Amanda Sanchez Machado, Elen R.R. Teixeira, Adriana S. Carneiro, Rogério J.M.B. Júnior, Vânia A. Vicente and Rachel B. Caligiorne*
Affiliation:
- Núcleo de Pós- Graduação e Pesquisa da Santa Casa de Belo Horizonte, MG,Brazil
Keywords: Dermatomycoses, leprosy, phaeohyphomycosis, Exophiala dermatitidis, mycological, DNA.
Abstract: Background: Subcutaneous phaeohyphomycosis is an infection caused by melanized fungi and is increasingly reported among immunosuppressive patients. The most commonly cited etiologic agent is Exophiala jeanselmei, followed by Alternaria spp. We present a case of subcutaneous phaeohyphomycosis in a 48-yearold woman, with a history of lepromatous leprosy, using corticosteroid in immunosuppressive doses due to a type 2 repetitive reaction leprosy outbreak.
Result and Discussion: The diagnosis was confirmed by fine-needle aspiration of the secretion, with subsequent direct mycological observations, culture and molecular analysis. The species agent was identified by culture and nucleotide sequences of ribosomal DNA as Exophiala dermatitidis.Export Options
About this article
Cite this article as:
Teixeira M. R. Márcia , Assunção B. Claudia, Lyon Sandra , Gomes R. Renata , Junior B.M. Hyllo , Rocha-Silva Fabiana, de Figueiredo M. Sônia, Machado Sanchez Amanda , Teixeira R.R. Elen , Carneiro S. Adriana, Júnior J.M.B. Rogério, Vicente A. Vânia and Caligiorne B. Rachel *, A Case of Subcutaneous Phaeohyphomycosis Associated with Leprosy, Infectious Disorders - Drug Targets 2017; 17 (3) . https://dx.doi.org/10.2174/1871526517666170530124905
DOI https://dx.doi.org/10.2174/1871526517666170530124905 |
Print ISSN 1871-5265 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3989 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Targeting Inflammatory Bowel Diseases by Nanocarriers Loaded with Small and Biopharmaceutical Anti-Inflammatory Drugs
Current Pharmaceutical Design New Imaging Tracers for the Infected Diabetic Foot (Nuclear and Optical Imaging)
Current Pharmaceutical Design Metastatic Brain Tumors: To Treat or Not to Treat, and with What?
Current Cancer Therapy Reviews Finding the Smoking Gun: Protein Tyrosine Phosphatases as Tools and Targets of Unicellular Microorganisms and Viruses
Current Medicinal Chemistry Involvement of Rat Hippocampal Astrocytes in β-Amyloid-Induced Angiogenesis and Neuroinflammation
Current Alzheimer Research Prospects for Clinical Introduction of Nitroimidazole Antibiotics for the Treatment of Tuberculosis
Current Pharmaceutical Design Patients with Hereditary Hemorrhagic Telangectasia (HHT) Exhibit a Deficit of Polymorphonuclear Cell and Monocyte Oxidative Burst and Phagocytosis: A Possible Correlation with Altered Adaptive Immune Responsiveness in HHT
Current Pharmaceutical Design Drugs Targeting Parasite Lysosomes
Current Pharmaceutical Design Clinical Applications of Choline PET/CT in Brain Tumors
Current Pharmaceutical Design The Neurovascular Protection Afforded by Delayed Local Hypothermia after Transient Middle Cerebral Artery Occlusion
Current Neurovascular Research Meet Our Associate Editorial Board Member
Current Psychopharmacology Neurotuberculosis: An Overview
Central Nervous System Agents in Medicinal Chemistry Metabolite Quantification in Tumours by Magnetic Resonance Spectroscopy: Objectives, Results and Perspectives
Current Medical Imaging Receptor Binding Ligands to Image Infection
Current Pharmaceutical Design Association of Metronidazole with Cancer: A Potential Risk Factor or Inconsistent Deductions?
Current Drug Metabolism Amantadine, Apomorphine and Zolpidem in the Treatment of Disorders of Consciousness
Current Pharmaceutical Design Tuberculosis and HIV Coinfection–the Challenge in the Prevention, Detection and Treatment of Tuberculosis
Current Bioinformatics Back Pain in Children and Adolescents: Etiology, Clinical Approach and Treatment
Current Pediatric Reviews Cranial Ultrasound - Optimizing Utility in the NICU
Current Pediatric Reviews A Review of Various Machine Learning Techniques for Brain Tumor Detection from MRI Images
Current Medical Imaging