Abstract
Background: Subcutaneous phaeohyphomycosis is an infection caused by melanized fungi and is increasingly reported among immunosuppressive patients. The most commonly cited etiologic agent is Exophiala jeanselmei, followed by Alternaria spp. We present a case of subcutaneous phaeohyphomycosis in a 48-yearold woman, with a history of lepromatous leprosy, using corticosteroid in immunosuppressive doses due to a type 2 repetitive reaction leprosy outbreak.
Result and Discussion: The diagnosis was confirmed by fine-needle aspiration of the secretion, with subsequent direct mycological observations, culture and molecular analysis. The species agent was identified by culture and nucleotide sequences of ribosomal DNA as Exophiala dermatitidis.Keywords: Dermatomycoses, leprosy, phaeohyphomycosis, Exophiala dermatitidis, mycological, DNA.
Graphical Abstract
Infectious Disorders - Drug Targets
Title:A Case of Subcutaneous Phaeohyphomycosis Associated with Leprosy
Volume: 17 Issue: 3
Author(s): Márcia M. R. Teixeira, Claudia B. Assunção, Sandra Lyon, Renata R. Gomes, Hyllo B.M. Junior, Fabiana Rocha-Silva, Sônia M. de Figueiredo, Amanda Sanchez Machado, Elen R.R. Teixeira, Adriana S. Carneiro, Rogério J.M.B. Júnior, Vânia A. Vicente and Rachel B. Caligiorne*
Affiliation:
- Núcleo de Pós- Graduação e Pesquisa da Santa Casa de Belo Horizonte, MG,Brazil
Keywords: Dermatomycoses, leprosy, phaeohyphomycosis, Exophiala dermatitidis, mycological, DNA.
Abstract: Background: Subcutaneous phaeohyphomycosis is an infection caused by melanized fungi and is increasingly reported among immunosuppressive patients. The most commonly cited etiologic agent is Exophiala jeanselmei, followed by Alternaria spp. We present a case of subcutaneous phaeohyphomycosis in a 48-yearold woman, with a history of lepromatous leprosy, using corticosteroid in immunosuppressive doses due to a type 2 repetitive reaction leprosy outbreak.
Result and Discussion: The diagnosis was confirmed by fine-needle aspiration of the secretion, with subsequent direct mycological observations, culture and molecular analysis. The species agent was identified by culture and nucleotide sequences of ribosomal DNA as Exophiala dermatitidis.Export Options
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Cite this article as:
Teixeira M. R. Márcia , Assunção B. Claudia, Lyon Sandra , Gomes R. Renata , Junior B.M. Hyllo , Rocha-Silva Fabiana, de Figueiredo M. Sônia, Machado Sanchez Amanda , Teixeira R.R. Elen , Carneiro S. Adriana, Júnior J.M.B. Rogério, Vicente A. Vânia and Caligiorne B. Rachel *, A Case of Subcutaneous Phaeohyphomycosis Associated with Leprosy, Infectious Disorders - Drug Targets 2017; 17 (3) . https://dx.doi.org/10.2174/1871526517666170530124905
DOI https://dx.doi.org/10.2174/1871526517666170530124905 |
Print ISSN 1871-5265 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3989 |
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