Abstract
Introduction: Multiple meningiomas growth in patients under cyproterone acetate (CPA) is now well known. However, time between initial CPA intake and diagnosis remains unclear.
Methods: The exposure time differs in each reported case: from 2 to 10 years. We present the case of an old man with acute visual impairment caused by an unusual bilateral optic nerve compression by three likely planum sphenoidale meningiomas rapidly induced by the admistration of CPA for prostatic adenocarinoma. Results and Conclusion: This case is the first reported with a short exposure time (7 months) to CPA treatment before diagnosis of multiple meningiomas and stabilization on clinical follow-up after CPA treatment discontinuation.Keywords: Papilledema, bilateral optic nerve compression, multiple meningiomas, cyproterone acetate, pharmacovigilance, exposure time.
Graphical Abstract
Current Drug Safety
Title:An Uncommon Case of Symptomatic Multiple Meningiomas with Bilateral Compressive Optic Neuropathy Rapidly Induced under Cyprotero ne Acetate Treatment
Volume: 12 Issue: 2
Author(s): Chafik Keilani*Samir Abada
Affiliation:
- CHNO des quinze-vingts, Faculty of Medicine Pierre et Marie Curie (Paris VI), 28 Rue de Charenton, 75 571 Paris,France
Keywords: Papilledema, bilateral optic nerve compression, multiple meningiomas, cyproterone acetate, pharmacovigilance, exposure time.
Abstract: Introduction: Multiple meningiomas growth in patients under cyproterone acetate (CPA) is now well known. However, time between initial CPA intake and diagnosis remains unclear.
Methods: The exposure time differs in each reported case: from 2 to 10 years. We present the case of an old man with acute visual impairment caused by an unusual bilateral optic nerve compression by three likely planum sphenoidale meningiomas rapidly induced by the admistration of CPA for prostatic adenocarinoma. Results and Conclusion: This case is the first reported with a short exposure time (7 months) to CPA treatment before diagnosis of multiple meningiomas and stabilization on clinical follow-up after CPA treatment discontinuation.Export Options
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Cite this article as:
Keilani Chafik*, Abada Samir, An Uncommon Case of Symptomatic Multiple Meningiomas with Bilateral Compressive Optic Neuropathy Rapidly Induced under Cyprotero ne Acetate Treatment, Current Drug Safety 2017; 12 (2) . https://dx.doi.org/10.2174/1574886312666170523154548
DOI https://dx.doi.org/10.2174/1574886312666170523154548 |
Print ISSN 1574-8863 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3911 |
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