Abstract
The perpetuation of healthy vision is paramount in an individual. It has been observed that various drug delivery systems have been fabricated to develop vision quality in individuals. Systemic ocular drug therapies have limited efficacy due to poor bioavailability, systemic and toxic side effects and low patient compliance. Various drug systems which follow the ocular route of administration are manufactured to achieve optimized bioavailability along with better patient compliance. Ocular implant is one such example. It is divided into biodegradable and non-biodegradable drug delivery systems wherein the former is more beneficial. This review aims to demonstrate the current momentum in the formulation and optimization of various biodegradable ocular drug delivery systems and its characteristics.
Keywords: Biodegradable polymers, biodegradable implants, advancements, pharmaceutical technology, ocular implants, bioavailability.
Graphical Abstract
Current Drug Delivery
Title:Recent Advancemnts in Biodegradable Ocular Implants
Volume: 15 Issue: 2
Author(s): Swati Mittal and Oshin Miranda*
Affiliation:
- Department of Pharmacology, University of Minnesota (Medical School Twin cities), Minnesota, 55455,United States
Keywords: Biodegradable polymers, biodegradable implants, advancements, pharmaceutical technology, ocular implants, bioavailability.
Abstract: The perpetuation of healthy vision is paramount in an individual. It has been observed that various drug delivery systems have been fabricated to develop vision quality in individuals. Systemic ocular drug therapies have limited efficacy due to poor bioavailability, systemic and toxic side effects and low patient compliance. Various drug systems which follow the ocular route of administration are manufactured to achieve optimized bioavailability along with better patient compliance. Ocular implant is one such example. It is divided into biodegradable and non-biodegradable drug delivery systems wherein the former is more beneficial. This review aims to demonstrate the current momentum in the formulation and optimization of various biodegradable ocular drug delivery systems and its characteristics.
Export Options
About this article
Cite this article as:
Mittal Swati and Miranda Oshin *, Recent Advancemnts in Biodegradable Ocular Implants, Current Drug Delivery 2018; 15 (2) . https://dx.doi.org/10.2174/1567201814666170508104254
DOI https://dx.doi.org/10.2174/1567201814666170508104254 |
Print ISSN 1567-2018 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5704 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Hyaluronan/Hyaladherins - a Promising Axis for Targeted Drug Delivery in Cancer
Current Drug Delivery Metabolic Features of Melanoma: A Gold Mine of New Therapeutic Targets?
Current Cancer Drug Targets Anti-HER2 Cancer Therapy and Cardiotoxicity
Current Pharmaceutical Design Emerging Anabolic Treatments in Osteoporosis
Current Drug Safety Identification of Small Molecule Sulfonic Acids as Ecto-5'-Nucleotidase Inhibitors
Medicinal Chemistry Mechanisms and Immunological Roles of Apoptosis in Molluscs
Current Pharmaceutical Design Age-Related Argonaute Loading of Ribosomal RNA Fragments
MicroRNA Potential Benefits of Glitazones for Cancer and Vascular Disease
Current Drug Therapy Hybrid SPECT/CT Imaging in Neurology
Current Radiopharmaceuticals Steroid Sulfatase Inhibitors: Their Potential in the Therapy of Breast Cancer
Current Medicinal Chemistry - Anti-Cancer Agents Current Pharmacological Approaches to Prevent and Treat Post- Menopausal Osteoporosis
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery (Discontinued) Synthesis and In-Vitro Antitumor Activity of Selected 7-Fluoro-6-(4-methyl-1-piperazinyl)-2-(thiosubstituted)-4(3H)-quinazolinones
Letters in Organic Chemistry Xenobiotic Sulphation and its Variability During Inflammation: a Factor in Adverse Drug Reactions?
Current Drug Metabolism Evaluation of Non-Coding RNAs as Potential Targets in Head and Neck Squamous Cell Carcinoma Cancer Stem Cells
Current Drug Targets Editorials (Pharmacogenomics in Primary Care: A Crucial Entry Point for Global Personalized Medicine?)
Current Pharmacogenomics and Personalized Medicine Unlocking the Molecular Mechanisms of DNA Repair and Platinum Drug Resistance in Cancer Chemotherapy
Current Drug Therapy ENaC in the Brain - Future Perspectives and Pharmacological Implications
Current Molecular Pharmacology Implication of Aberrant Glycosylation in Cancer and Use of Lectin for Cancer Biomarker Discovery
Protein & Peptide Letters An Efficient Four-Step Approach Toward Fused Triazino[1,6-a] Quinazolines
Combinatorial Chemistry & High Throughput Screening Human Serum Albumin Conjugated Biomolecules for Cancer Molecular Imaging
Current Pharmaceutical Design