Abstract
Background: Despite the substantial progress over the time, malaria remains a major public health concern and causing hundreds of thousands of deaths. Resistance to the available antimalarial therapy increases threat to the global public health.
Objective: Overview of currently available antimalarials. Method: Literary survey. Results: The summarized data about different types of antimalarial therapies and their efficiency and modes of action. Conclusion: Despite the seemingly large number of the drugs currently available for malaria treatment, this arsenal is limited due to the narrow variation of their mechanism of action.Keywords: Malaria, Antimalarial drugs, Drug resistance, Mechanism of action, Antimalarial therapy, Plasmodium.
Graphical Abstract
Current Topics in Medicinal Chemistry
Title:An Overview of Currently Available Antimalarials
Volume: 17 Issue: 19
Author(s): Nikolay Yu. Gorobets*, Yuriy V. Sedash, Brajendra K. Singh, Poonam and Brijesh Rathi*
Affiliation:
- Department of Chemistry of Heterocyclic Compounds, State Scientific Institution “Institute for Single Crystals”, National Academy of Science of Ukraine, Nauky ave. 60, Kharkiv, 61001,Ukraine
- Department of Chemistry, Hansraj College University Enclave, University of Delhi, Delhi-110007,India
Keywords: Malaria, Antimalarial drugs, Drug resistance, Mechanism of action, Antimalarial therapy, Plasmodium.
Abstract: Background: Despite the substantial progress over the time, malaria remains a major public health concern and causing hundreds of thousands of deaths. Resistance to the available antimalarial therapy increases threat to the global public health.
Objective: Overview of currently available antimalarials. Method: Literary survey. Results: The summarized data about different types of antimalarial therapies and their efficiency and modes of action. Conclusion: Despite the seemingly large number of the drugs currently available for malaria treatment, this arsenal is limited due to the narrow variation of their mechanism of action.Export Options
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Cite this article as:
Gorobets Yu. Nikolay*, Sedash V. Yuriy, Singh K. Brajendra, Poonam and Rathi Brijesh*, An Overview of Currently Available Antimalarials, Current Topics in Medicinal Chemistry 2017; 17 (19) . https://dx.doi.org/10.2174/1568026617666170130123520
DOI https://dx.doi.org/10.2174/1568026617666170130123520 |
Print ISSN 1568-0266 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4294 |
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