Distinct Biomarkers for Early Diagnosis of Diabetic Nephropathy

Title:Distinct Biomarkers for Early Diagnosis of Diabetic Nephropathy

Volume: 13 Issue: 6

Author(s): Lalit Kishore, Navpreet Kaur and Randhir Singh*

Affiliation:

• M.M. College of Pharmacy, Maharishi Markandeshwar University, Mullana-Ambala, Haryana 133207,India

Keywords: Albuminuria, biomarkers, diabetic nephropathy, diagnostic method, emerging biomarkers, albumin.

Abstract: Background: Diabetic nephropathy (DN) is one of the foremost causes of mortality in diabetic patients as a result of increased urinary albumin excretion (UAE) rate and compromised renal function.

Introduction: Determination of increased excretion of albumin in urine chiefly attribute to the onset and progression of DN. However, due to certain limitations of albuminuria, the search for more sensitive, specific and reliable renal biomarkers is required for early prediction of DN.

Methods: Bibliographic investigation was made to scrutinize the data reporting relevant biomarkers associated with DN and may be used to predict the onset and progression of nephropathy.

Result and Conclusion: Optimization of biomarkers for a clinical situation requires a prospective validation in large numbers of patients with diabetic nephropathy and needs to be performed in different critically ill populations.

Cite this article as:

Kishore Lalit , Kaur Navpreet and Singh Randhir*, Distinct Biomarkers for Early Diagnosis of Diabetic Nephropathy, Current Diabetes Reviews 2017; 13 (6) . https://dx.doi.org/10.2174/1573399812666161207123007