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Current Drug Safety

Editor-in-Chief

ISSN (Print): 1574-8863
ISSN (Online): 2212-3911

Research Article

Fatal Intoxications in the North of Portugal: 12 Years of Retrospective Analysis

Author(s): Emanuele A. Alves, Pedro Brandao, Teresa Magalhaes, Felix Carvalho and Ricardo J. Dinis-Oliveira

Volume 12, Issue 1, 2017

Page: [39 - 45] Pages: 7

DOI: 10.2174/1574886311666160724212407

Price: $65

Abstract

Background: Fatal intoxications are a topic of great relevance in today’s society. They typically occur by accidental or voluntary ingestion, but its characterization by a forensic perspective was not fully explored.

Objective: This study retrospectively reviews fatal intoxication cases autopsied at the northern forensic medicine services of Portugal, between 2001 and 2013.

Method: For this purpose, we analyzed postmortem forensic medical reports with positive qualitative analysis for xenobiotics.

Results: A total of 27,778 autopsy reports were analyzed, of which 1,269 cases fulfilled the selection criteria, representing 4.6% of total number of individuals autopsied during the period under analysis. Men were involved in most of the cases (73.8%) and most individuals were adults with ages between 36 and 65 years old (57.0%). The highest incidences were medicines (22.9%) and alcohol (15.8%), followed by their association. Cases of fatal intoxications involving opioids come on fifth place (5.8%) namely due to accidental overdoses. Moreover, intoxications appeared as the leading cause of death in reports concerning accidental etiology, with drugs and alcohol associations having a great expression.

Conclusion: Due to morbidity and relevant number of fatal cases, risk prevention measures, such as public health policies should be implemented to reduce the number of intoxications.

Keywords: Alcohol, fatal intoxications, forensic autopsy, medicines, xenobiotics.


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