Abstract
Freezing of gait (FOG) is a heterogeneous symptom. Studies of treatment for FOG are scarce. Levodopa and monoamine oxidase inhibitors (rasagiline and selegiline) have shown effective improvement for FOG. Other drugs, such as L-threo-3, 4-dihydroxyphenylserine, amantadine, and botulinum toxin have exhibited some beneficial effects. The present review summarizes the potential drug treatment for FOG in Parkinsonism.
Keywords: Drug treatment, freezing of gait, Levodopa, Parkinson’s disease, Parkinsonism.
Graphical Abstract
Current Neuropharmacology
Title:Freezing of Gait in Parkinsonism and its Potential Drug Treatment
Volume: 14 Issue: 4
Author(s): Li-Li Zhang, S. Duff Canning and Xiao-Ping Wang
Affiliation:
Keywords: Drug treatment, freezing of gait, Levodopa, Parkinson’s disease, Parkinsonism.
Abstract: Freezing of gait (FOG) is a heterogeneous symptom. Studies of treatment for FOG are scarce. Levodopa and monoamine oxidase inhibitors (rasagiline and selegiline) have shown effective improvement for FOG. Other drugs, such as L-threo-3, 4-dihydroxyphenylserine, amantadine, and botulinum toxin have exhibited some beneficial effects. The present review summarizes the potential drug treatment for FOG in Parkinsonism.
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Cite this article as:
Zhang Li-Li, Canning Duff S. and Wang Xiao-Ping, Freezing of Gait in Parkinsonism and its Potential Drug Treatment, Current Neuropharmacology 2016; 14 (4) . https://dx.doi.org/10.2174/1570159X14666151201190040
DOI https://dx.doi.org/10.2174/1570159X14666151201190040 |
Print ISSN 1570-159X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6190 |
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