T-cell Activation Induces Dynamic Changes in miRNA Expression Patterns in CD4 and CD8 T-cell Subsets

Title:T-cell Activation Induces Dynamic Changes in miRNA Expression Patterns in CD4 and CD8 T-cell Subsets

Volume: 4 Issue: 2

Author(s): Nato Teteloshvili, Katarzyna Smigielska-Czepiel, Bart-Jan Kroesen, Elisabeth Brouwer, Joost Kluiver, Annemieke M. H. Boots and Anke van den Berg

Affiliation:

Keywords: Activation, antibodies, immune, microRNA, miRNA regulation, T cell.

Abstract: T-cell activation affects microRNA (miRNA) expression in T-cell subsets. However, little is known about the kinetics of miRNA regulation and possible differences between CD4 and CD8 T cells. In this study we set out to analyze the kinetics of activation-induced expression regulation of twelve pre-selected miRNAs. The dynamics of the expression of these miRNAs was studied in sorted CD4 and CD8 CD45RO- T cells of healthy individuals stimulated with

Cite this article as:

Teteloshvili Nato, Smigielska-Czepiel Katarzyna, Kroesen Bart-Jan, Brouwer Elisabeth, Kluiver Joost, Boots M. H. Annemieke and van den Berg Anke, T-cell Activation Induces Dynamic Changes in miRNA Expression Patterns in CD4 and CD8 T-cell Subsets, MicroRNA 2015; 4 (2) . https://dx.doi.org/10.2174/2211536604666150819194636