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Applied Clinical Research, Clinical Trials and Regulatory Affairs

Editor-in-Chief

ISSN (Print): 2213-476X
ISSN (Online): 2213-4778

Two Cases of Glucose-6-phosphate Dehydrogenase Deficiency Presenting as Symptomatic Methemoglobinemia with Persistently Low Saturations After Fava Bean Ingestion in United Arab Emirates

Author(s): Aisha Alkhaaldi, Majid Al Teneiji, Muhammad Faisal Khanani, Mustafa Baroudi, Altaf Jamil, Omar Trad, Layla Al Reyami and Najam Ahmed Awan

Volume 1, Issue 3, 2014

Page: [176 - 179] Pages: 4

DOI: 10.2174/2213476X0103150707122135

Price: $65

Abstract

We report two cases of one previously healthy child and another known to have G6PD deficiency, who presented with desaturation despite their stable clinical appearance, which later was attributed to methemoglobinemia (MetHb) that was precipitated by fava beans ingestion.

When hemolytic crisis occurs, certain G6PD deficient patients might develop cyanosis and show evidence of concurrent methemoglobinemia.

In conclusion, Methemoglobinemia is a rare but important cause of persistently low saturation.

Keywords: Acute hemolysis, Favism, Glucose-6-phosphate dehydrogenase deficiency, Methemoglobinemia.


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