Emerging Alternative Functions for the Auxiliary Subunits of the Voltage- Gated Calcium Channels

Title:Emerging Alternative Functions for the Auxiliary Subunits of the Voltage- Gated Calcium Channels

Volume: 8

Author(s): Franz Hofmann, Anouar Belkacemi and Veit Flockerzi

Affiliation:

Keywords: Auxiliary subunits, heart, insulin secretion, neurons, non-smooth muscle cells, pain perception voltage-gated calcium channel.

Abstract: Voltage gated calcium channels (Cav) are composed of up to five proteins: The ion conducting pore subunit α1 and the auxiliary subunits α₂, δ, β, and γ. Recent reports show that Cavα1 and Cavβ comprise the calcium channel core complex and that β, α2 δ and γ may serve additional roles that are independent of the Cavα₁ subunit. This short review will summarize these emerging functions.

Cite this article as:

Hofmann Franz, Belkacemi Anouar and Flockerzi Veit, Emerging Alternative Functions for the Auxiliary Subunits of the Voltage- Gated Calcium Channels, Current Molecular Pharmacology 2015; 8 (2) . https://dx.doi.org/10.2174/1874467208666150507110202