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Current Pharmaceutical Analysis

Editor-in-Chief

ISSN (Print): 1573-4129
ISSN (Online): 1875-676X

Critical Review of Malondialdehyde Analysis in Biological Samples

Author(s): Maryam Khoubnasabjafari, Khalil Ansarin and Abolghasem Jouyban

Volume 12, Issue 1, 2016

Page: [4 - 17] Pages: 14

DOI: 10.2174/1573412911666150505185343

Price: $65

Abstract

Malondialdehyde (MDA) is one of the most common biomarkers of oxidative stress and is used for the diagnosis of many diseases. This work aims to review the reaction used for the derivatization of MDA, the parameters affecting adduct formation, and a number of recently published analytical methods for quantification of MDA in biological samples. A brief discussion of the reliability of MDA as an oxidative stress biomarker is also provided.

Keywords: Oxidative stress, biomarker, malondialdehyde, serum analysis, bioanalysis, review.

Graphical Abstract


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