Abstract
Polyphenols are an extensive group of substances present in plants. Animals and humans achieve them through the diet. Polyphenols have been related to several processes, such as oxidative stress and signaling pathways modulating gene expression that promote an anti-inflammatory environment. Moreover, polyphenols also have a possible role in the protection of several diseases, including major depression. Depression is an important public-health problem with a multifactorial etiology and lots of pathways that can be altered in affected subjects. Moreover, this disease can be affected by exercise, sleep and diet. There are animal works studying polyphenols and depression, but human studies are scarce. This review summarizes recent evidences in relation to the effects of polyphenols as antidepressant agents in the depression.
Keywords: Antidepressant, depression, inflammation, oxidative stress, public-health, polyphenol.
Current Pharmaceutical Biotechnology
Title:Polyphenols and Depression: from Chemistry to Medicine
Volume: 16 Issue: 3
Author(s): Antoni Sureda and Silvia Tejada
Affiliation:
Keywords: Antidepressant, depression, inflammation, oxidative stress, public-health, polyphenol.
Abstract: Polyphenols are an extensive group of substances present in plants. Animals and humans achieve them through the diet. Polyphenols have been related to several processes, such as oxidative stress and signaling pathways modulating gene expression that promote an anti-inflammatory environment. Moreover, polyphenols also have a possible role in the protection of several diseases, including major depression. Depression is an important public-health problem with a multifactorial etiology and lots of pathways that can be altered in affected subjects. Moreover, this disease can be affected by exercise, sleep and diet. There are animal works studying polyphenols and depression, but human studies are scarce. This review summarizes recent evidences in relation to the effects of polyphenols as antidepressant agents in the depression.
Export Options
About this article
Cite this article as:
Sureda Antoni and Tejada Silvia, Polyphenols and Depression: from Chemistry to Medicine, Current Pharmaceutical Biotechnology 2015; 16 (3) . https://dx.doi.org/10.2174/1389201016666150118133313
DOI https://dx.doi.org/10.2174/1389201016666150118133313 |
Print ISSN 1389-2010 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4316 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Fluorine-18 Labeled Amino Acids for Oncologic Imaging with Positron Emission Tomography
Current Topics in Medicinal Chemistry A Review on the Phytochemicals, Ethnomedicine Uses and Pharmacology of Ficus Species
Current Traditional Medicine Modulating Fatty Acid Metabolism and the AMP-Activated Protein Kinase Pathway as a Target for Obesity Therapy
Current Medicinal Chemistry - Immunology, Endocrine & Metabolic Agents Specific Active Immunotherapy of Cancer: Potential and Perspectives
Reviews on Recent Clinical Trials Editorial [Hot Topic: Molecular Tools in Cancer Diagnosis and Therapy Guest Editor: Riyaz Basha]
Current Medicinal Chemistry Biological Strategies to Enhance Rotator Cuff Healing.
Current Stem Cell Research & Therapy Synthesis of Biologically Potent Novel 5-(2-bromopyridin-3-yl-amino)-2- alkyl/aryl-isoindoline-1,3-dione Analogs Via Buchwald-Hartwig C-N Coupling Reaction
Letters in Organic Chemistry In Silico Design of Protein Kinase Inhibitors: Successes and Failures
Anti-Cancer Agents in Medicinal Chemistry Current Status of Leukemia Cytotherapy - Exploitation with Immune Cells
Current Stem Cell Research & Therapy Humans Entrain to Sunlight - Impact of Social Jet Lag on Disease and Implications for Critical Illness
Current Pharmaceutical Design CFTR and MDR: ABC Transporters with Homologous Structure but Divergent Function
Current Genomics Is Brain-Derived Neurotrophic Factor: A Common Link Between Neurodegenerative Disorders and Cancer?
Current Alzheimer Research PP2A in the Regulation of Cell Motility and Invasion
Current Protein & Peptide Science Review on Documented Medicinal Plants used for the Treatment of Cancer
Current Traditional Medicine Molecular Design and Clinical Development of VEGFR Kinase Inhibitors
Current Topics in Medicinal Chemistry Synthesis and Anticancer Studies of Novel N-benzyl Pyridazino ne Derivatives
Letters in Drug Design & Discovery Effect of Alpha-1-Acid Glycoprotein Binding on Pharmacokinetics and Pharmacodynamics
Current Drug Metabolism Antiangiogenic Therapy
Current Pharmaceutical Design Immune Response Manipulation: Recombinant Immunoreceptors Endow T-Cells with Predefined Specificity
Current Pharmaceutical Design Molecular Imaging: Translation from Rats to Dogs and Humans
Current Medical Imaging