Abstract
Most of the people suffering malaria do not know how complex is that disease and how hard searchers are working to fight against it. Some of these people are dying from malaria while still efficient drug combinations should have save their lives. But these drugs were not available for them when needed, or the diagnosis was wrong, or the drugs were fake, or the doctor was untrained, or the patient had no money. Should this terrible reality preclude the need for continuous research to develop new antimalarial drugs? Should people working in laboratories located in non-endemic countries adapt their project to that reality? Malaria eradication, then elimination was announced and broadcasted in the late sixties, and later forgotten. From that failure due to chloroquine resistance and after decades of less arrogant work, billions of dollars are on the table again to claim this goal. There were bed nets, drugs, vaccine and communication as starters, let’s hope people in endemic countries will be winners.
Keywords: Antimalarial drugs, chemistry, disease, dogma, endemic areas, malaria, patients, plasmodium.
Graphical Abstract
Current Topics in Medicinal Chemistry
Title:New Anti-Malarial Drugs: Who Cares?
Volume: 14 Issue: 14
Author(s): Stephane Picot, Philippe M. Loiseau and Anne-Lise Bienvenu
Affiliation:
Keywords: Antimalarial drugs, chemistry, disease, dogma, endemic areas, malaria, patients, plasmodium.
Abstract: Most of the people suffering malaria do not know how complex is that disease and how hard searchers are working to fight against it. Some of these people are dying from malaria while still efficient drug combinations should have save their lives. But these drugs were not available for them when needed, or the diagnosis was wrong, or the drugs were fake, or the doctor was untrained, or the patient had no money. Should this terrible reality preclude the need for continuous research to develop new antimalarial drugs? Should people working in laboratories located in non-endemic countries adapt their project to that reality? Malaria eradication, then elimination was announced and broadcasted in the late sixties, and later forgotten. From that failure due to chloroquine resistance and after decades of less arrogant work, billions of dollars are on the table again to claim this goal. There were bed nets, drugs, vaccine and communication as starters, let’s hope people in endemic countries will be winners.
Export Options
About this article
Cite this article as:
Picot Stephane, Loiseau M. Philippe and Bienvenu Anne-Lise, New Anti-Malarial Drugs: Who Cares?, Current Topics in Medicinal Chemistry 2014; 14 (14) . https://dx.doi.org/10.2174/1568026614666140808121039
DOI https://dx.doi.org/10.2174/1568026614666140808121039 |
Print ISSN 1568-0266 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4294 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Editorial (Thematic Issue: Novel Insights on Aortic Aneurysm)
Current Pharmaceutical Design Influence of Essential Trace Minerals and Micronutrient Insufficiencies on Harmful Metal Overload in a Mongolian Patient with Multiple Sclerosis
Current Aging Science Pharmacological Treatment of Cognitive Symptoms in Alzheimer's Disease
Current Psychopharmacology Human Cognitive and Neuro-Psychiatric Bio-Markers in the Cardiac Peri-Operative Patient
Current Molecular Medicine Usefulness of CSF Biomarkers in Predicting the Progression of Amnesic and Nonamnesic Mild Cognitive Impairment to Alzheimer’s Disease
Current Aging Science Vitamin D and Vascular Disease
Current Vascular Pharmacology Landmark-Based Shape Analysis on Middle Cerebral Intracranial Aneurysms: A Geometric Morphometrics Approach to Infer Natural History
Current Neurovascular Research Low-Molecular-Weight-Heparins: A Review of Literature
Vascular Disease Prevention (Discontinued) Renal Heat Shock Proteins Over-Expression Due to Anabolic Androgenic Steroids Abuse
Mini-Reviews in Medicinal Chemistry Physical Activity and Body Mass Index in Relation to Infertility in Women
Reviews on Recent Clinical Trials Vitamin B<sub>12</sub> Deficiency Among the Healthy Jordanian Adult Population: Diagnostic Levels, Symptomology and Risk Factors
Endocrine, Metabolic & Immune Disorders - Drug Targets Treatment of Type 1 Diabetic Patients with Glucagon-Like Peptide-1 (GLP-1) and GLP-1R Agonists
Current Diabetes Reviews Pegylated Naloxone in the Treatment of Persistent Opioid-Induced Constipation in Patients with Hematological Malignancies
Cardiovascular & Hematological Agents in Medicinal Chemistry Evaluation of Anticancer, Antibacterial and Antioxidant Properties of a Medicinally Treasured Fern Tectaria coadunata with its Phytoconstituents Analysis by HR-LCMS
Anti-Cancer Agents in Medicinal Chemistry The Role of Mitochondria in Brain Aging and the Effects of Melatonin
Current Neuropharmacology Abnormal Insulin Signaling: Early Detection of Silent Coronary Artery Disease-Erectile Dysfunction?
Current Pharmaceutical Design The Science of Hypoglycemia in Patients with Diabetes
Current Diabetes Reviews New Perspectives of Infections in Cardiovascular Disease
Current Cardiology Reviews Polyphenols and Aging
Current Aging Science Diagnostic Issues in Early-Onset Obsessive-Compulsive Disorder and their Treatment Implications
Current Neuropharmacology