Nanoparticle-Delivered Quercetin for Cancer Therapy

Title:Nanoparticle-Delivered Quercetin for Cancer Therapy

Volume: 14 Issue: 6

Author(s): Ke Men, Xingmei Duan, Xia Wei Wei, Ma Ling Gou, Mei Juan Huang, Li Juan Chen, Zhi Yong Qian and Yu Quan Wei

Affiliation:

Keywords: Cancer therapy, nanoparticle, nanotechnology, quercetin.

Abstract: Quercetin, a natural protective bioflavonoid, possesses diverse pharmacologic effects, such as antioxidant, anti-inflammatory, anti-proliferative, and anti-angiogenic activities. Recently, quercetin’s effect in cancer prevention and treatment was recognized. However, the poor water solubility and low-bioavailability of quercetin limit its clinical use in cancer therapy. Nanotechnology provides a method to create novel formulations for hydrophobic drug. Nanoparticles-delivered quercetin has attracted many attentions for its enhanced anticancer potential and promising clinical application. This review will discuss the application of nanotechnology in quercetin delivery for cancer therapy.

Cite this article as:

Men Ke, Duan Xingmei, Wei Wei Xia, Gou Ling Ma, Huang Juan Mei, Chen Juan Li, Qian Yong Zhi and Wei Quan Yu, Nanoparticle-Delivered Quercetin for Cancer Therapy, Anti-Cancer Agents in Medicinal Chemistry 2014; 14 (6) . https://dx.doi.org/10.2174/1871520614666140521122932