Abstract
Phytochemistry accords with phytochemicals which are obtained from a plant source. In recent years, there is a great insistence to phytochemical constituents as they are devoid of adverse reactions. On account of lack of modern scientific evidence for their basis of action on diseases, a crude extract is not well accepted. But due to the adverse side effects & increasing failure of modern drugs to cure the ailments, the attention has been turned back towards ancient systems of medicine, such as, Ayurveda, Unani and Chinese. Consequently, plants have once again attained the centre stage in the efforts aimed at developing effective drugs for diseases incurable by modern medicine system. Hence, the present issue was aimed to point out the in detail study of the phytochemical compounds including but not limited to isolation, structure elucidation, in silico studies(molecular docking, QSAR etc) and assessment of therapeutic potential which would aid in understanding the chemical structures better as therapeutic agent.
Keywords: Phytochemistry, in silico studies, QSAR, drug likeness, bioactives.
Current Topics in Medicinal Chemistry
Title:Editorial (Thematic Issue: From Phytochemistry to Medicinal Chemistry: Isolation, Semisynthesis, Evaluation and Computational Studies)
Volume: 14 Issue: 8
Author(s): Rajeev K. Singla, G. Varadaraj Bhat and Humberto Gonzalez-Diaz
Affiliation:
Keywords: Phytochemistry, in silico studies, QSAR, drug likeness, bioactives.
Abstract: Phytochemistry accords with phytochemicals which are obtained from a plant source. In recent years, there is a great insistence to phytochemical constituents as they are devoid of adverse reactions. On account of lack of modern scientific evidence for their basis of action on diseases, a crude extract is not well accepted. But due to the adverse side effects & increasing failure of modern drugs to cure the ailments, the attention has been turned back towards ancient systems of medicine, such as, Ayurveda, Unani and Chinese. Consequently, plants have once again attained the centre stage in the efforts aimed at developing effective drugs for diseases incurable by modern medicine system. Hence, the present issue was aimed to point out the in detail study of the phytochemical compounds including but not limited to isolation, structure elucidation, in silico studies(molecular docking, QSAR etc) and assessment of therapeutic potential which would aid in understanding the chemical structures better as therapeutic agent.
Export Options
About this article
Cite this article as:
Singla K. Rajeev, Bhat Varadaraj G. and Gonzalez-Diaz Humberto, Editorial (Thematic Issue: From Phytochemistry to Medicinal Chemistry: Isolation, Semisynthesis, Evaluation and Computational Studies), Current Topics in Medicinal Chemistry 2014; 14 (8) . https://dx.doi.org/10.2174/1568026614666140324145723
DOI https://dx.doi.org/10.2174/1568026614666140324145723 |
Print ISSN 1568-0266 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4294 |
![](/images/wayfinder.jpg)
- Author Guidelines
- Bentham Author Support Services (BASS)
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Intraoperative Targeted Optical Imaging: A Guide towards Tumor-Free Margins in Cancer Surgery
Current Pharmaceutical Biotechnology Metronomic Therapy for Multi Relapsed/Refractory Lymphoma. A Pilot Study
Current Angiogenesis (Discontinued) The Biological Activity of the Novel Vinca Alkaloids 4-chlorochablastine and 4-chlorochacristine
Current Cancer Drug Targets In Vivo Inhibition of the Estrogen Sulfatase Enzyme and Growth of DMBA-Induced Mammary Tumors by Melatonin
Current Cancer Drug Targets Histone Variants and Composition in the Developing Brain: Should MeCP2 Care?
Current Topics in Medicinal Chemistry Drug Transporters and Multiple Drug Resistance in the Most Common Pediatric Solid Tumors
Current Drug Metabolism Puerarin Stimulates Osteogenic Differentiation and Bone Formation Through the ERK1/2 and p38-MAPK Signaling Pathways
Current Molecular Medicine Benzofuran-Based Estrogen Receptor α Modulators as Anti-Cancer Therapeutics: In Silico and Experimental Studies
Current Medicinal Chemistry Viral Origins of Human Cancer
Current Medicinal Chemistry Pharmacological Exploitation of Indole-3-Carbinol to Develop Potent Antitumor Agents
Mini-Reviews in Medicinal Chemistry Synthesis and Biological Evaluation of Estradiol-Core Derivatives Bearing a Fused γ-Lactone as Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 1
Current Enzyme Inhibition Indole-based, Antiproliferative Agents Targeting Tubulin Polymerization
Current Topics in Medicinal Chemistry Targeting Transient Receptor Potential Channels in Cardiometabolic Diseases and Myocardial Ischemia Reperfusion Injury
Current Drug Targets PERK-opathies: An Endoplasmic Reticulum Stress Mechanism Underlying Neurodegeneration
Current Alzheimer Research Roles of miRNA in the Initiation and Development of Colorectal Carcinoma
Current Pharmaceutical Design Sulfonamides and Sulfonylated Derivatives as Anticancer Agents
Current Cancer Drug Targets Pathophysiology of NASH: Perspectives for a Targeted Treatment
Current Pharmaceutical Design Antitumor Therapeutic Strategies Based on the Targeting of Epidermal Growth Factor-Induced Survival Pathways
Current Drug Targets The Genetic Landscapes of Inflammation-Driven Gastrointestinal Tract Cancers
Current Pharmaceutical Design Anti-Gene Strategies to Down-Regulate Gene Expression in Mammalian Cells
Current Pharmaceutical Design