Abstract
A new series of 2-cyanomethylthienotriazolopyrimidines has been synthesized in good yield through a facile method using substituted aminothiophene-3-carbonitrile as building block and cyanoacetic acid hydrazide as reagent in one framework. The structure of the synthesized compounds was established on the basis of their mass and spectral data.
Keywords: 2-Aminothiophene-3-carbonitrile, iminoethers, iminithieopyrimidin-3-ylamine, cyanoacetic acid hydrazide, thienotriazolopyrimidine.
Graphical Abstract
Letters in Organic Chemistry
Title:A Convenient Synthesis of New 2-Cyanomethylthieno[3,2-e][1,2,4]- triazolo[1,5-c]pyrimidine Derivatives
Volume: 11 Issue: 6
Author(s): Dhiab Jabli, Khaireddine Dridi and Mohamed L. El Efrit
Affiliation:
Keywords: 2-Aminothiophene-3-carbonitrile, iminoethers, iminithieopyrimidin-3-ylamine, cyanoacetic acid hydrazide, thienotriazolopyrimidine.
Abstract: A new series of 2-cyanomethylthienotriazolopyrimidines has been synthesized in good yield through a facile method using substituted aminothiophene-3-carbonitrile as building block and cyanoacetic acid hydrazide as reagent in one framework. The structure of the synthesized compounds was established on the basis of their mass and spectral data.
Export Options
About this article
Cite this article as:
Jabli Dhiab, Dridi Khaireddine and El Efrit Mohamed L., A Convenient Synthesis of New 2-Cyanomethylthieno[3,2-e][1,2,4]- triazolo[1,5-c]pyrimidine Derivatives, Letters in Organic Chemistry 2014; 11 (6) . https://dx.doi.org/10.2174/1570178611666140311005612
DOI https://dx.doi.org/10.2174/1570178611666140311005612 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
![](/images/wayfinder.jpg)
- Author Guidelines
- Bentham Author Support Services (BASS)
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Pleuroscopy Early Experience in the Exudative Pleural Effusion of Unknown Etiology
Current Respiratory Medicine Reviews Structure of Cytochrome P450s and Personalized Drug
Current Medicinal Chemistry Fatty Acid (FA) Compositions and Trans Content of Frequently Consumed Edible Oils and Fats from Iran’ Market
Current Nutrition & Food Science Synthesis and Functionalization of Corroles. An Insight on Their Nonlinear Optical Absorption Properties
Current Organic Synthesis A Profile of Current Methods for DNA Methylation Analysis
Current Analytical Chemistry Design, Synthesis and Cytotoxic Activity of Spiro(oxindole-3-3'- pyrrolidine) Derivatives
Letters in Drug Design & Discovery Empyema and Bronchopleural Fistula Following Lung Resection
Current Respiratory Medicine Reviews MicroRNAs in Cancer: Small Molecules, Big Chances
Anti-Cancer Agents in Medicinal Chemistry Bilirubin Chemistry and Metabolism; Harmful and Protective Aspects
Current Pharmaceutical Design Bergenin - A Biologically Active Scaffold: Nanotechnological Perspectives
Current Topics in Medicinal Chemistry Extraction of Triacylglycerols and Fatty Acids Using Supercritical Fluids - Review
Current Analytical Chemistry Third Generation Radiopharmaceuticals for Imaging and Targeted Therapy
Current Pharmaceutical Analysis Synthesis of N-glycosylated Dihydropyrimidones – A Novel Approach Using Epoxy Sugar
Letters in Organic Chemistry Small Molecules' Multi-Metabolic Pathways Prediction Using Physico- Chemical Features and Multi-Task Learning Method.
Current Bioinformatics Multiple Emulsions: An Overview
Current Drug Delivery Inorganic Nanoparticles for In Vitro Cancer Diagnosis: A Patent Review
Recent Patents on Nanomedicine Radioiodinated Ginger Compounds (6-gingerol and 6-shogaol) and Incorporation Assays on Breast Cancer Cells
Anti-Cancer Agents in Medicinal Chemistry NF-κB Down–regulation and PARP Cleavage by novel 3-α-butyryloxy-β-boswellic Acid Results in Cancer Cell Specific Apoptosis and in vivo Tumor Regression
Anti-Cancer Agents in Medicinal Chemistry Phosphoproteomics: Challenges and Opportunities
Current Proteomics Nanostructures as Promising Tools for Delivery of Antimicrobial Peptides
Mini-Reviews in Medicinal Chemistry