Abstract
α-Helixes are important structural motifs of protein three dimension structures and are largely involved in protein- protein interactions. This review covers the recent advances of the peptide stabilizing methodologies and introduces their applications in cancer research.
Keywords: Cancer therapy, protein-protein interaction, stapled peptide, α-helix.
Current Medicinal Chemistry
Title:Peptides-Staple Method Development and Its Application in Cancer Therapy
Volume: 21 Issue: 21
Author(s): Q.Z. Zhang, Y. Tian, Y.Z. Lao and Z.-G. Li
Affiliation:
Keywords: Cancer therapy, protein-protein interaction, stapled peptide, α-helix.
Abstract: α-Helixes are important structural motifs of protein three dimension structures and are largely involved in protein- protein interactions. This review covers the recent advances of the peptide stabilizing methodologies and introduces their applications in cancer research.
Export Options
About this article
Cite this article as:
Zhang Q.Z., Tian Y., Lao Y.Z. and Li Z.-G., Peptides-Staple Method Development and Its Application in Cancer Therapy, Current Medicinal Chemistry 2014; 21 (21) . https://dx.doi.org/10.2174/0929867321666140205130835
DOI https://dx.doi.org/10.2174/0929867321666140205130835 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Voltage-Dependent Potassium Channels Kv1.3 and Kv1.5 in Human Cancer
Current Cancer Drug Targets Role of Nuclear Imaging in Cardiac Amyloidosis Management: Clinical Evidence and Review of Literature
Current Medical Imaging Role of PPAR in Cardiovascular Diseases
Recent Patents on Cardiovascular Drug Discovery The Comparison of Different Planes in Breast Ultrasonography
Current Medical Imaging Synergistic Approaches to Clinical Oncology Biomarker Discovery
Current Topics in Medicinal Chemistry EGFR Mutation Testing in Non-Small Cell Lung Cancer
Current Respiratory Medicine Reviews Recent Developments in Targeting Breast Cancer Stem Cells
Recent Patents on Regenerative Medicine Understanding the Multifaceted Role of Ectonucleotide Pyrophosphatase/Phosphodiesterase 2 (ENPP2) and its Altered Behaviour in Human Diseases
Current Molecular Medicine Epithelial Mesenchymal Transition in Cancer Progression: Prev entive Phytochemicals
Recent Patents on Anti-Cancer Drug Discovery Recent Advances in Enone and NO-Releasing Derivatives of Oleanolic Acid with Anti-cancer Activity
Mini-Reviews in Organic Chemistry Editorial: Multiple Myeloma Immunotherapies
Current Cancer Drug Targets Ovarian Toxicity: From Environmental Exposure to Chemotherapy
Current Pharmaceutical Design Trace of Long Non-Coding RNAs in Signaling Pathways in Thyroid Cancer
Current Signal Transduction Therapy Preface
Current Pharmaceutical Design The Role of COX-2 in Acute Pain and the Use of Selective COX-2 Inhibitors for Acute Pain Relief
Current Pharmaceutical Design Regulation of Mammalian UDP-Glucuronosyltransferases
Current Drug Metabolism Nitric Oxide and Arginine Dysregulation: A Novel Pathway to Pulmonary Hypertension in Hemolytic Disorders
Current Molecular Medicine Cyclodextrin Complexation of Meclizine Hydrochloride and its Influence on the Solubility for its Repurposing
Drug Delivery Letters Targeting the Akt Kinase to Modulate Survival, Invasiveness and Drug Resistance of Cancer Cells
Current Medicinal Chemistry Synthesis and Evaluation of Antioxidant and Cytotoxicity of the N-Mannich Base of Berberine Bearing Benzothiazole Moieties
Anti-Cancer Agents in Medicinal Chemistry