Abstract
Probiotics are nowadays frequently used by patients with inflammatory bowel disease, however literature data are conflicting related to their importance.
In mild to moderate ulcerative colitis probiotics can be used effectively in induction and maintaining remission, and prevention of pouchitis. As the other side of the shield, there is not sufficient evidence to support the use of probiotics in daily clinical practice in Crohn’s disease.
The aim of the present review is to provide help for clinicians about the probiotic use in patients with inflammatory bowel disease. The comparison of literature data is limited by the large number of probiotic strains, various combined preparations, and different doses applied in the clinical studies. Small number of comparable protocols and lack of standardization encumber the analysis of study results.
Keywords: Probiotics, inflammatory bowel disease.
Current Pharmaceutical Design
Title:Probiotics in the Management of Crohn's disease and Ulcerative Colitis
Volume: 20 Issue: 28
Author(s): Katalin Mullner, Pal Miheller, Laszlo Herszenyi and Zsolt Tulassay
Affiliation:
Keywords: Probiotics, inflammatory bowel disease.
Abstract: Probiotics are nowadays frequently used by patients with inflammatory bowel disease, however literature data are conflicting related to their importance.
In mild to moderate ulcerative colitis probiotics can be used effectively in induction and maintaining remission, and prevention of pouchitis. As the other side of the shield, there is not sufficient evidence to support the use of probiotics in daily clinical practice in Crohn’s disease.
The aim of the present review is to provide help for clinicians about the probiotic use in patients with inflammatory bowel disease. The comparison of literature data is limited by the large number of probiotic strains, various combined preparations, and different doses applied in the clinical studies. Small number of comparable protocols and lack of standardization encumber the analysis of study results.
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Cite this article as:
Mullner Katalin, Miheller Pal, Herszenyi Laszlo and Tulassay Zsolt, Probiotics in the Management of Crohn's disease and Ulcerative Colitis, Current Pharmaceutical Design 2014; 20 (28) . https://dx.doi.org/10.2174/13816128113196660727
DOI https://dx.doi.org/10.2174/13816128113196660727 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
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