Characteristics Other than the Diagnostic Criteria Associated with Metabolic Syndrome: An Overview

Title:Characteristics Other than the Diagnostic Criteria Associated with Metabolic Syndrome: An Overview

Volume: 12 Issue: 4

Author(s): Niki Katsiki, Vasilios G. Athyros, Asterios Karagiannis and Dimitri P. Mikhailidis

Affiliation:

Keywords: Arterial stiffness, cytokines, diagnostic criteria, lipids, metabolic syndrome, platelets, renal dysfunction, uric acid.

Abstract: Metabolic syndrome (MetS), a cluster of dyslipidaemia, central obesity, hypertension and/or insulin resistance, is associated with increased cardiovascular disease (CVD) type 2 diabetes risk. Different diagnostic criteria for MetS have been proposed but in 2009 a joint statement by several scientific societies was released.

Apart from the diagnostic criteria, MetS has also been associated with other risk factors including waist to hip ratio, high density lipoprotein dysfunction, small dense low density lipoprotein, postprandial hypertriglyceridaemia, lipoprotein (a), uric acid, liver function tests, prothrombotic factors, cytokines, adipokines, vitamin D, arterial stiffness, renal dysfunction, nephrolithiasis, polycystic ovary syndrome, obstructive sleep apnea.

We discuss the extensive list of MetS-associated factors that may influence vascular risk. Furthermore, we discuss the impact of frequently prescribed drugs (e.g. hypolipidaemic agents) on these variables. These effects may need to be taken into consideration when treating MetS patients.

Cite this article as:

Katsiki Niki, Athyros G. Vasilios, Karagiannis Asterios and Mikhailidis P. Dimitri, Characteristics Other than the Diagnostic Criteria Associated with Metabolic Syndrome: An Overview, Current Vascular Pharmacology 2014; 12 (4) . https://dx.doi.org/10.2174/15701611113119990131