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Micro and Nanosystems

Editor-in-Chief

ISSN (Print): 1876-4029
ISSN (Online): 1876-4037

Application of Microfluidic Technology for Studying Islet Physiology and Pathophysiology

Author(s): Yong Wang, Joshua E. Mendoza-Elias, James J. McGarrigle, Mohammad Nourmohammadzadeh, Qian Wang, Ze Li, Brian Rady, Feng Feng, Meirigeng Qi, Joe F. Lo, David T. Eddington and Jose Oberholzer

Volume 5, Issue 3, 2013

Page: [216 - 223] Pages: 8

DOI: 10.2174/1876402911305030009

Price: $65

Abstract

This review outlines the current status of microfluidic devices used to study the physiology and pathophysiology of pancreatic islets of Langerhans, mainly focusing on the design features and specialized applications of existing microfluidic devices, as well as their advantages and limitations. This review then briefly concludes by describing future perspectives on ways to improve and implement microfluidic technology for islet study.

Keywords: β-cells, Insulin Secretion, Islet of Langerhans, Microencapsulation, Microfluidics, Oxygen, Transplantation.


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